prion protein Bovine antibody

Overview


	Antigen:	Prion protein
	Antibody Type:	Monoclonal
	Application:	Western Blotting (WB), ELISA
	Reactivity:	Bovine
	Host:	Mouse
	Quantity:	500 µg (Product variants)
	Price:	1.400,00 € (Plus shipping costs and VAT)
	Order number:	ABIN123806
	Availability:	Ships in 1 to 2 days.

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Additional Information: prion protein Bovine antibody

Antigen	Prion protein
Reactivity	Bovine
Antibody Type	Monoclonal
Format	Liquid. Supplied as a 1 mg/ml solution in culture medium supplemented with FBS.
Description	Monoclonal antibody (mAb)3C10 is a murine IgG2a subtype antibody.
Clone	Clone 3C10
Host	Mouse
Specificity	MAb 3C10 recognizes the sequence G108 QWNKP113 of the bovine prion protein (human PrP: amino acids 97-102). This sequence near the N-terminal proteinase K digestion site is conserved to some extent in known mammalian prion proteins.

Application Details: prion protein Bovine antibody

Application	Western Blotting (WB), ELISA
Application Notes	MAb 3C10 detects recombinant PrPc from cattle, sheep, hamster, mouse and human in Western blots. It also detects the bovine prion protein in immunoblots of brain homogenates of healthy and BSE-affected animals, and the partly refolded recombinant bovine PrP in ELISA applications.
Storage	Store at -80 °C, avoid freeze/thaw cycles. Shipped on dry ice. Shelf Life: 12 months.
Restrictions	For Research Use only.

Publications: prion protein Bovine antibody

Publications

Kim, Umetani, Matsui et al.:
"Antigenic characterization of an abnormal isoform of prion protein using a new diverse panel of monoclonal antibodies."
In: Virology , Vol. 320, Issue 1, pp. 40-51, 2004/01 (PubMed)

Kuebler, Oesch, Raeber:
"Diagnosis of prion diseases."
In: British medical bulletin , Vol. 66, pp. 267-79, 2003/01 (PubMed)

Schaller, Fatzer, Stack et al.:
"Validation of a western immunoblotting procedure for bovine PrP(Sc) detection and its use as a rapid surveillance method for the diagnosis of bovine spongiform encephalopathy (BSE)."
In: Acta neuropathologica , Vol. 98, Issue 5, pp. 437-43, 1999/01 (PubMed)

Images: prion protein Bovine antibody

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Product variants

prion protein Bovine antibody (Format: Liquid. Supplied as a 1 mg/ml solution in culture medium...

External Information: prion protein Bovine antibody

Google Scholar	Find more references for clone clone 3C10 on Google Scholar™
EMBL Harvester	Search human, mouse or rat genome for antigen alpha-bPrion Protein 3C10 (anti-PrPc) L pack (Bioinformatic Harvester (EMBL))