The following gene names and symbols are associated with antigen A Disintegrin-Like and Metalloprotease with Thrombospondin Type 1 Motif 7 across different species:

ADAM metallopeptidase with thrombospondin type 1 motif, 8 (ADAMTS8), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), ADAM metallopeptidase with thrombospondin type 1 motif, 7 (ADAMTS7), a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 (Adamts7), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (Adamts5), ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) (ADAMTS5)

Other aliases include:

METH2, ADAM-TS8, FLJ41712, ADMP-2, ADAMTS11, FLJ36738, ADAM-TS7, DKFZp434H204, ADAMTS7B, ADAMTS5, ADAMTS-11

On the protein level the following designations are being used for antigen A Disintegrin-Like and Metalloprotease with Thrombospondin Type 1 Motif 7:

ADAM metallopeptidase with thrombospondin type 1 motif, 8 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8 – ADAM metallopeptidase with thrombospondin type 1 motif, 5 – aggrecanase-2 – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) – ADAM metallopeptidase with thrombospondin type 1 motif, 7 – COMPase – a disintegrin and metalloprotease with thrombospondin motifs-7 preproprotein – a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 7 – metalloprotease – ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) – a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)

A Disintegrin-Like and Metalloprotease with Thrombospondin Type 1 Motif 7 fulfills a number of functions:

heparin binding – integrin binding – low affinity phosphate transmembrane transporter activity – metal ion binding – metalloendopeptidase activity – peptidase activity – zinc ion binding – hydrolase activity – metallopeptidase activity

A Disintegrin-Like and Metalloprotease with Thrombospondin Type 1 Motif 7 is relevant to the following processes:

negative regulation of cell proliferation – proteolysis

Locations for A Disintegrin-Like and Metalloprotease with Thrombospondin Type 1 Motif 7:

extracellular region – proteinaceous extracellular matrix – cell surface – extracellular matrix

Source: NCBI Entrez Gene, Gene Ontology