The following gene names and symbols are associated with antigen Ataxia Telangiectasia Mutated across different species:

ataxia telangiectasia mutated (ATM), ataxia telangiectasia mutated homolog (human) (Atm), telomere fusion (tefu), ataxia telangiectasia mutated (atm), ataxia telangiectasia mutated (EDI_100660), ataxia telangiectasia mutated (CpipJ_CPIJ001772), ataxia telangiectasia mutated (BDBG_08252), ataxia telangiectasia mutated (PAAG_02532), ataxia telangiectasia mutated (MCYG_05088), ataxia telangiectasia mutated (VDBG_06833), ataxia telangiectasia mutated (atm) (ACLA_015700), ataxia telangiectasia mutated (atm) (AaeL_AAEL014900), ataxia telangiectasia mutated (MGYG_07634), ataxia telangiectasia mutated (PGTG_14279)

Other aliases include:

AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1, MGC74674, DKFZp781A0353, AI256621, C030026E19Rik, ATM, Tefu, atm/tefu, dATM, tef, DmelCG6535, CG6535, Xatm

On the protein level the following designations are being used for antigen Ataxia Telangiectasia Mutated:

ataxia telangiectasia mutated – AT mutated – serine-protein kinase ATM – TEL1, telomere maintenance 1, homolog – human phosphatidylinositol 3-kinase homolog – ataxia telangiectasia mutated (includes complementation groups A, C and D) – ataxia telangiectasia gene mutated in human beings – telomere fusion – CG6535-PB – tefu-PB – drosophila ATM – Ataxia telangiectasia gene mutated in human beings – ATM (ataxia telangiectasia mutated) – chunp9624 – ataxia telangiectasia mutated protein – Serine-protein kinase ATM – ataxia-telangiectasia mutated – serine-protein kinase ATM-like – ataxia telangiectasia mutated (atm)

Ataxia Telangiectasia Mutated fulfills a number of functions:

1-phosphatidylinositol-3-kinase activity – ATP binding – DNA binding – nucleotide binding – protein N-terminus binding – protein serine/threonine kinase activity – transferase activity – kinase activity – phosphotransferase activity, alcohol group as acceptor – protein kinase activity – molecular_function – inositol or phosphatidylinositol kinase activity

Ataxia Telangiectasia Mutated is relevant to the following processes:

DNA repair – cell cycle – cell death – mitotic cell cycle spindle assembly checkpoint – reciprocal meiotic recombination – response to DNA damage stimulus – response to ionizing radiation – signal transduction – DNA damage checkpoint – DNA damage response, signal transduction resulting in induction of apoptosis – brain development – female gamete generation – heart development – lipoprotein catabolic process – negative regulation of apoptosis – neuron apoptosis – positive regulation of neuron apoptosis – protein amino acid phosphorylation – somitogenesis – G2/M transition DNA damage checkpoint – cell cycle checkpoint – chromatin silencing at telomere – chromosome organization – phosphorylation – telomere capping – telomere maintenance – apoptosis – response to hypoxia

Locations for Ataxia Telangiectasia Mutated:

cytoplasmic membrane-bounded vesicle – nucleoplasm – nucleus – cytoplasmic vesicle – spindle – cytoplasm – cellular_component

Source: NCBI Entrez Gene, Gene Ontology

anti-Ataxia Telangiectasia Mutated (ATM) antibody (ABIN95420) cited in Medical hypotheses

anti-Ataxia Telangiectasia Mutated (ATM) antibody (ABIN95420) cited in Seminars in pediatric neurology

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