The following gene names and symbols are associated with antigen B-Cell Leukemia/Lymphoma 5 across different species:

B-cell leukemia/lymphoma 2 (Bcl2), B-cell leukemia/lymphoma 6 (Bcl6), B-cell leukemia/lymphoma 2 (bcl2)

Other aliases include:

Bcl-2, AW986256, C430015F12Rik, D630044D05Rik, D830018M01Rik, Bcl5

On the protein level the following designations are being used for antigen B-Cell Leukemia/Lymphoma 5:

apoptosis regulator Bcl-2 – OTTMUSP00000024915 – B-cell lymphoma 6 protein homolog – B-cell leukemia/lymphoma 5 – Bcl2 – zBlp2

B-Cell Leukemia/Lymphoma 5 fulfills a number of functions:

BH domain binding – protein binding – protein heterodimerization activity – protein phosphatase 2A binding – protein phosphatase binding – transcription activator activity – transcription factor binding – DNA binding – chromatin DNA binding – chromatin binding – metal ion binding – nucleic acid binding – sequence-specific DNA binding – transcription repressor activity – zinc ion binding

B-Cell Leukemia/Lymphoma 5 is relevant to the following processes:

B cell differentiation – B cell homeostasis – B cell lineage commitment – B cell proliferation – CD8-positive, alpha-beta T cell lineage commitment – G1/S transition of mitotic cell cycle – T cell differentiation – T cell differentiation in the thymus – T cell homeostasis – T cell lineage commitment – actin filament organization – anti-apoptosis – apoptosis – apoptosis in response to endoplasmic reticulum stress – axon regeneration – axonogenesis – behavioral fear response – branching involved in ureteric bud morphogenesis – cell aging – cell death – cell growth – cell morphogenesis – cell proliferation – cell-cell adhesion – cellular calcium ion homeostasis – cochlear nucleus development – developmental growth – developmental pigmentation – digestive tract morphogenesis – ear development – endoplasmic reticulum calcium ion homeostasis – focal adhesion assembly – gland morphogenesis – glomerulus development – growth – hair follicle morphogenesis – hemopoiesis – homeostasis of number of cells within a tissue – immune system development – kidney development – leukocyte homeostasis – lymphocyte homeostasis – lymphoid progenitor cell differentiation – male gonad development – melanin metabolic process – melanocyte differentiation – mesenchymal cell development – metanephros development – negative regulation of apoptosis – negative regulation of calcium ion transport into cytosol – negative regulation of cell growth – negative regulation of cell migration – negative regulation of cell proliferation – negative regulation of mitotic cell cycle – negative regulation of myeloid cell apoptosis – negative regulation of neuron apoptosis – negative regulation of ossification – negative regulation of osteoblast proliferation – negative regulation of retinal cell programmed cell death – neuron apoptosis – oocyte development – organ growth – organ morphogenesis – ossification – ovarian follicle development – oxygen and reactive oxygen species metabolic process – peptidyl-serine phosphorylation – peptidyl-threonine phosphorylation – pigment granule organization – pigmentation – positive regulation of catalytic activity – positive regulation of cell growth – positive regulation of cell proliferation – positive regulation of developmental pigmentation – positive regulation of melanocyte differentiation – positive regulation of multicellular organism growth – positive regulation of neuron maturation – positive regulation of peptidyl-serine phosphorylation – positive regulation of skeletal muscle fiber development – positive regulation of smooth muscle cell migration – positive regulation of transcription – post-embryonic development – protein amino acid dephosphorylation – protein polyubiquitination – regulation of apoptosis – regulation of calcium ion transport – regulation of catalytic activity – regulation of cell cycle – regulation of cell-matrix adhesion – regulation of developmental pigmentation – regulation of gene expression – regulation of glycoprotein biosynthetic process – regulation of mitochondrial membrane permeability – regulation of mitochondrial membrane potential – regulation of nitrogen utilization – regulation of programmed cell death – regulation of protein localization – regulation of protein stability – regulation of viral genome replication – release of cytochrome c from mitochondria – renal system process – response to UV-B – response to acid – response to chemical stimulus – response to cytokine stimulus – response to drug – response to external stimulus – response to gamma radiation – response to glucocorticoid stimulus – response to hydrogen peroxide – response to oxidative stress – response to protein stimulus – response to steroid hormone stimulus – response to toxin – spleen development – thymus development – ureteric bud development – Rho protein signal transduction – T-helper 2 type immune response – actin cytoskeleton organization – erythrocyte development – germinal center formation – negative regulation of Rho protein signal transduction – negative regulation of T-helper 2 cell differentiation – negative regulation of T-helper 2 type immune response – negative regulation of cell differentiation – negative regulation of cell-matrix adhesion – negative regulation of isotype switching to IgE isotypes – negative regulation of mast cell cytokine production – negative regulation of transcription from RNA polymerase II promoter – positive regulation of B cell proliferation – positive regulation of cellular component movement – protein localization – regulation of Rho GTPase activity – regulation of cell proliferation – regulation of inflammatory response – regulation of memory T cell differentiation – regulation of transcription – spermatogenesis – transcription – negative regulation of caspase activity

Locations for B-Cell Leukemia/Lymphoma 5:

cytoplasm – cytosol – endoplasmic reticulum – endoplasmic reticulum membrane – integral to membrane – intracellular – membrane – membrane fraction – microsome – mitochondrial membrane – mitochondrial outer membrane – mitochondrion – myelin sheath – nuclear membrane – nucleus

Source: NCBI Entrez Gene, Gene Ontology