The following gene names and symbols are associated with antigen BCL2 Binding Component 3 across different species:

BCL2 binding component 3 (BBC3), BCL2 binding component 3 (Bbc3), BCL2 binding component 3 (bbc3)

Other aliases include:

JFY1, PUMA, PUMA/JFY1, BBC3

On the protein level the following designations are being used for antigen BCL2 Binding Component 3:

BCL2 binding component 3 – Bcl-2 binding component 3 – BH3-only – OTTMUSP00000025190 – Puma

BCL2 Binding Component 3 fulfills a number of functions:

protein binding – positive regulation of apoptosis – positive regulation of caspase activity

BCL2 Binding Component 3 is relevant to the following processes:

DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis – activation of caspase activity – induction of apoptosis – negative regulation of growth – release of cytochrome c from mitochondria – apoptosis – negative regulation of cell growth – positive regulation of apoptosis – regulation of apoptosis

Locations for BCL2 Binding Component 3:

mitochondrial outer membrane – mitochondrion – mitochondrial envelope

Source: NCBI Entrez Gene, Gene Ontology