The following gene names and symbols are associated with antigen BCL2-Associated X Protein across different species:

BCL2-associated X protein (BAX), BCL2-associated X protein (Bax), Bcl2-associated X protein (Bax), bcl2-associated X protein, a (baxa), BCL2-associated X protein (bax-A), BCL2-associated X protein (bax), BCL2-associated X protein (LOC100355675)

Other aliases include:

BCL2L4, bax, fj16e01, wu:fc50b10, wu:fj16e01, BAX, bax-A, xBax, xlbax, MGC76049, BAX-ALPHA

On the protein level the following designations are being used for antigen BCL2-Associated X Protein:

BCL2-associated X protein – apoptosis regulator BAX – Bcl2-associated X protein – bcl2-associated X protein – bcl2-associated X protein, a – zBax1 – bax zeta – BCL2-associated protein

BCL2-Associated X Protein fulfills a number of functions:

BH3 domain binding – lipid binding – protein heterodimerization activity – protein homodimerization activity – protein binding – chaperone binding – heat shock protein binding – positive regulation of apoptosis – positive regulation of caspase activity – regulation of apoptosis – response to cadmium ion – response to methylmercury

BCL2-Associated X Protein is relevant to the following processes:

B cell apoptosis – DNA fragmentation involved in apoptosis – activation of caspase activity by cytochrome c – cleavage of lamin – establishment or maintenance of transmembrane electrochemical gradient – induction of apoptosis by extracellular signals – induction of apoptosis by intracellular signals – induction of retinal programmed cell death – mitochondrial fragmentation during apoptosis – mitochondrial fusion – negative regulation of survival gene product expression – nuclear fragmentation during apoptosis – positive regulation of neuron apoptosis – protein homooligomerization – regulation of apoptosis – regulation of mitochondrial membrane potential – regulation of protein heterodimerization activity – regulation of protein homodimerization activity – release of cytochrome c from mitochondria – release of matrix enzymes from mitochondria – response to toxin – transformed cell apoptosis – B cell homeostasis – B cell homeostatic proliferation – B cell negative selection – Sertoli cell proliferation – T cell homeostatic proliferation – activation of caspase activity – apoptosis – apoptosis in response to endoplasmic reticulum stress – apoptotic mitochondrial changes – blood vessel remodeling – cell proliferation – cellular response to UV – cerebral cortex development – development of secondary sexual characteristics – fertilization – germ cell development – germ cell programmed cell death – glycosphingolipid metabolic process – homeostasis of number of cells – homeostasis of number of cells within a tissue – hypothalamus development – induction of apoptosis – induction of apoptosis in response to chemical stimulus – kidney development – leukocyte homeostasis – limb morphogenesis – male gonad development – myeloid cell homeostasis – negative regulation of anti-apoptosis – negative regulation of cell proliferation – negative regulation of fibroblast proliferation – negative regulation of neuron apoptosis – negative regulation of peptidyl-serine phosphorylation – nervous system development – neuron apoptosis – neuron migration – odontogenesis of dentine-containing tooth – ovarian follicle development – positive regulation of B cell apoptosis – positive regulation of apoptosis – positive regulation of apoptosis involved in mammary gland involution – positive regulation of calcium ion transport into cytosol – positive regulation of pigmentation during development – positive regulation of release of sequestered calcium ion into cytosol – post-embryonic camera-type eye morphogenesis – post-embryonic development – protein insertion into mitochondrial membrane during induction of apoptosis – reduction of endoplasmic reticulum calcium ion concentration – regulation of caspase activity – regulation of cell cycle – regulation of mammary gland epithelial cell proliferation – regulation of mitochondrial membrane permeability – regulation of nitrogen utilization – response to DNA damage stimulus – response to acid – response to axon injury – response to gamma radiation – response to ionizing radiation – response to salt stress – response to wounding – retina development in camera-type eye – retinal cell programmed cell death – sex differentiation – spermatid differentiation – spermatogenesis – vagina development – cellular respiration – inner mitochondrial membrane organization – outer mitochondrial membrane organization – response to cocaine – response to copper ion – response to corticosterone stimulus – response to drug

Locations for BCL2-Associated X Protein:

cytoplasm – cytosol – endoplasmic reticulum – endoplasmic reticulum membrane – integral to membrane – membrane – mitochondrial outer membrane – mitochondrial permeability transition pore complex – mitochondrion – cytosolic part – intracellular – mitochondrial membrane – soluble fraction

Source: NCBI Entrez Gene, Gene Ontology