The following gene names and symbols are associated with antigen CASP8 Associated Protein 2 across different species:

caspase 8 associated protein 2 (CASP8AP2), CASP8 associated protein 2 (CASP8AP2), CASP8 associated protein 2 (casp8ap2), CASP8 associated protein 2 (LOC100232114), caspase 8 associated protein 2 (Casp8ap2)

Other aliases include:

CED-4, FLASH, RIP25, FLJ11208, KIAA1315, CASP8AP2, fc74h10, wu:fc74h10, zgc:113449, AA387232, mKIAA1315, D4Ertd659e

On the protein level the following designations are being used for antigen CASP8 Associated Protein 2:

caspase 8 associated protein 2 – human FLASH – FLASH homolog RIP25 – FLICE associated huge – CASP8 associated protein 2 – FLICE-associated huge protein – OTTMUSP00000005125 – CASP8-associated protein 2-like

CASP8 Associated Protein 2 fulfills a number of functions:

caspase activator activity – death receptor binding – identical protein binding – transcription corepressor activity – apoptotic protease activator activity – protein binding

CASP8 Associated Protein 2 is relevant to the following processes:

activation of caspase activity – cell cycle – induction of apoptosis via death domain receptors – regulation of transcription – signal transduction – biological_process – apoptosis – transcription

Locations for CASP8 Associated Protein 2:

cytoplasm – nucleus – cellular_component

Source: NCBI Entrez Gene, Gene Ontology