The following gene names and symbols are associated with antigen CASP8 and FADD-Like Apoptosis Regulator across different species:

CASP8 and FADD-like apoptosis regulator (CFLAR), CASP8 and FADD-like apoptosis regulator (Cflar), cellular FLICE-like inhibitory protein (C-FLIP), CASP8 and FADD-like apoptosis regulator (cflar)

Other aliases include:

CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1, Cash, Flip, Gm9845, c-Flip, AI646576, AU021929, MGC103395, 2310024N18Rik, A430105C05Rik, ENSMUSG00000072980, C-FLIP, MGC108616, Clarp1, CFLAR, DKFZp469E1815

On the protein level the following designations are being used for antigen CASP8 and FADD-Like Apoptosis Regulator:

CASP8 and FADD-like apoptosis regulator – usurpin beta – OTTHUMP00000207360 – inhibitor of FLICE – FADD-like anti-apoptotic molecule – caspase-related inducer of apoptosis – FLAME-1 – usurpin – caspase homolog – OTTMUSP00000021141 – OTTMUSP00000021142 – OTTMUSP00000021143 – OTTMUSP00000021144 – caspase-eight-related protein – MACH-related inducer of toxicity – FADD-like antiapoptotic molecule 1 – cellular FLICE-like inhibitory protein – caspase-like apoptosis regulatory protein – FLIP – FLICE-like inhibitory protein – flice/caspase-i inhibitory protein – CASP8 and FADD-like apoptosis regulator-like

CASP8 and FADD-Like Apoptosis Regulator fulfills a number of functions:

cysteine-type endopeptidase activity – protein binding

CASP8 and FADD-Like Apoptosis Regulator is relevant to the following processes:

anti-apoptosis – induction of apoptosis by extracellular signals – interspecies interaction between organisms – positive regulation of I-kappaB kinase/NF-kappaB cascade – proteolysis – regulation of apoptosis – apoptosis – negative regulation of apoptosis – negative regulation of caspase activity

Locations for CASP8 and FADD-Like Apoptosis Regulator:

cytoplasm

Source: NCBI Entrez Gene, Gene Ontology