The following gene names and symbols are associated with antigen Toll-Like Receptor 2 across different species:

toll-like receptor 2 (TLR2), toll-like receptor 2 (Tlr2)

Other aliases include:

TIL4, CD282, Ly105, TLR2, TLR2A, chTLR2

On the protein level the following designations are being used for antigen Toll-Like Receptor 2:

toll-like receptor 2 – toll/interleukin 1 receptor-like 4 – toll-like receptor 2 variant 1 – toll-like receptor 2 variant 2

Toll-Like Receptor 2 fulfills a number of functions:

Gram-positive bacterial binding – lipopolysaccharide receptor activity – peptidoglycan binding – protein binding – transmembrane receptor activity – receptor activity – Gram-positive bacterial cell surface binding – diacylated lipopeptide binding – lipoprotein binding – lipoteichoic acid binding – pattern recognition receptor activity – protein heterodimerization activity – triacylated lipopeptide binding

Toll-Like Receptor 2 is relevant to the following processes:

I-kappaB kinase/NF-kappaB cascade – MyD88-dependent toll-like receptor signaling pathway – cell surface pattern recognition receptor signaling pathway – chloramphenicol transport – induction of apoptosis – inflammatory response – innate immune response – positive regulation of interleukin-6 production – positive regulation of tumor necrosis factor production – response to molecule of fungal origin – signal transduction – defense response to Gram-positive bacterium – immune response – negative regulation of growth of symbiont in host – positive regulation of NF-kappaB transcription factor activity – positive regulation of leukocyte migration – positive regulation of macrophage cytokine production – positive regulation of nitric oxide biosynthetic process – response to bacterium – response to lipoteichoic acid – response to peptidoglycan – I-kappaB phosphorylation – cellular response to bacterial lipopeptide – cellular response to diacylated bacterial lipopeptide – cellular response to lipoteichoic acid – cellular response to peptidoglycan – cellular response to triacylated bacterial lipopeptide – defense response to bacterium – detection of diacylated bacterial lipopeptide – detection of triacylated bacterial lipopeptide – induction by symbiont of defense-related host nitric oxide production – microglial cell activation involved in immune response – negative regulation of interleukin-12 production – negative regulation of interleukin-17 production – pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity – positive regulation of NF-kappaB import into nucleus – positive regulation of chemokine production – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of interferon-beta production – positive regulation of interleukin-12 production – positive regulation of interleukin-18 production – positive regulation of interleukin-8 production – positive regulation of nitric-oxide synthase biosynthetic process – positive regulation of toll-like receptor signaling pathway – positive regulation of tumor necrosis factor biosynthetic process – response to bacterial lipoprotein – response to fatty acid – response to hypoxia – response to insulin stimulus – response to lipopolysaccharide – response to progesterone stimulus – response to toxin – toll-like receptor signaling pathway – detection of bacterial lipoprotein

Locations for Toll-Like Receptor 2:

external side of plasma membrane – integral to plasma membrane – plasma membrane – cytoplasmic vesicle – integral to membrane – intrinsic to membrane – membrane – Toll-like receptor 1-Toll-like receptor 2 protein complex – Toll-like receptor 2-Toll-like receptor 6 protein complex – cell surface – cytoplasm

Source: NCBI Entrez Gene, Gene Ontology