The following gene names and symbols are associated with antigen CD34 Class III across different species:

v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (Erbb2)

Other aliases include:

Neu, HER2, HER-2, c-neu, Erbb-2, c-erbB2, mKIAA3023

On the protein level the following designations are being used for antigen CD34 Class III:

v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog – Neu oncogene – OTTMUSP00000002540 – avian erythroblastosis oncogene B 2

CD34 Class III fulfills a number of functions:

ATP binding – kinase activity – nucleotide binding – protein binding – protein kinase activity – protein tyrosine kinase activity – receptor activity – receptor signaling protein tyrosine kinase activity – transferase activity – transmembrane receptor protein tyrosine kinase activity

CD34 Class III is relevant to the following processes:

cell surface receptor linked signal transduction – heart development – motor axon guidance – myelination – negative regulation of immature T cell proliferation in the thymus – nervous system development – neuromuscular junction development – peripheral nervous system development – protein amino acid phosphorylation – transmembrane receptor protein tyrosine kinase signaling pathway

Locations for CD34 Class III:

apical plasma membrane – cytoplasm – integral to membrane – membrane

Source: NCBI Entrez Gene, Gene Ontology

anti-CD34 Class III antibody (ABIN119525) cited in Journal of immunology (Baltimore, Md. : 1950)

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