The following gene names and symbols are associated with antigen CD80 across different species:

CD80 molecule (CD80)

Other aliases include:

LAB7, CD28LG, CD28LG1

On the protein level the following designations are being used for antigen CD80:

CD80 antigen – costimulatory factor CD80 – B-lymphocyte activation antigen B7 – costimulatory molecule variant IgV-CD80 – CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)

CD80 fulfills a number of functions:

coreceptor activity – protein binding – transcription activator activity

CD80 is relevant to the following processes:

T cell activation – cell-cell signaling – interspecies interaction between organisms – intracellular signaling cascade – positive regulation of T-helper 1 cell differentiation – positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process – positive regulation of interleukin-2 biosynthetic process – positive regulation of peptidyl-tyrosine phosphorylation – positive regulation of signal transduction – positive regulation of transcription

Locations for CD80:

integral to membrane – plasma membrane

Source: NCBI Entrez Gene, Gene Ontology