The following gene names and symbols are associated with antigen Caspase Recruitment Domain Family, Member 8 across different species:

caspase recruitment domain family, member 8 (CARD8)

Other aliases include:

NDPP, DACAR, Dakar, NDPP1, TUCAN, CARDINAL, FLJ18119, FLJ18121, KIAA0955, MGC57162, DKFZp779L0366, CARD8, DKFZp468E032

On the protein level the following designations are being used for antigen Caspase Recruitment Domain Family, Member 8:

caspase recruitment domain family, member 8 – CARD8 isoform T47 – CARD8 isoform T51 – CARD8 isoform T60 – apoptotic protein NDPP1 – CARD inhibitor of NF-kappaB-activating ligands – tumor up-regulated CARD-containing antagonist of caspase nine – Caspase recruitment domain-containing protein 8

Caspase Recruitment Domain Family, Member 8 fulfills a number of functions:

NACHT domain binding – caspase activator activity – protein binding – protein homodimerization activity

Caspase Recruitment Domain Family, Member 8 is relevant to the following processes:

negative regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of caspase activity – positive regulation of interleukin-1 beta secretion – regulation of apoptosis

Locations for Caspase Recruitment Domain Family, Member 8:

cytoplasm – intracellular – nucleus

Source: NCBI Entrez Gene, Gene Ontology