The following gene names and symbols are associated with antigen Chemokine (C-C Motif) Ligand 8 across different species:

chemokine (C-C motif) ligand 2 (CCL2), small inducible cytokine A24 (LOC100354652)

Other aliases include:

HC11, MCAF, MCP1, MCP-1, SCYA2, GDCF-2, SMC-CF, HSMCR30, MGC9434

On the protein level the following designations are being used for antigen Chemokine (C-C Motif) Ligand 8:

small inducible cytokine A2 – monocyte secretory protein JE – monocyte chemoattractant protein-1 – monocyte chemotactic and activating factor – small inducible cytokine subfamily A (Cys-Cys), member 2 – small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je) – small inducible cytokine A24

Chemokine (C-C Motif) Ligand 8 fulfills a number of functions:

CCR2 chemokine receptor binding – G-protein-coupled receptor binding – chemokine activity – protein kinase activity – signal transducer activity

Chemokine (C-C Motif) Ligand 8 is relevant to the following processes:

G-protein signaling, coupled to cyclic nucleotide second messenger – JAK-STAT cascade – anti-apoptosis – cell adhesion – cellular calcium ion homeostasis – chemotaxis – cytokine-mediated signaling pathway – humoral immune response – inflammatory response – macrophage chemotaxis – monocyte chemotaxis – organ morphogenesis – positive regulation of endothelial cell proliferation – protein amino acid phosphorylation – response to bacterium – transforming growth factor beta receptor signaling pathway – vascular endothelial growth factor receptor signaling pathway – viral genome replication

Locations for Chemokine (C-C Motif) Ligand 8:

cell soma – cytoplasm – extracellular region – extracellular space

Source: NCBI Entrez Gene, Gene Ontology