The following gene names and symbols are associated with antigen Checkpoint Kinase 1 across different species:

CHK1 checkpoint homolog (S. pombe) (CHEK1), checkpoint kinase 1 homolog (S. pombe) (Chek1), CHK1 checkpoint homolog (S. pombe) (Chek1), STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) (STT3A), Chk1 checkpoint kinase (LOC398191), serine/threonine-protein kinase chk1 (ANI_1_2436074), serine/threonine-protein kinase chk1 (AOR_1_768154), serine/threonine-protein kinase Chk1 (PTRG_04183), serine/threonine-protein kinase chk1 (SJAG_01680), serine/threonine-protein kinase chk1 (PAAG_04978), serine/threonine-protein kinase chk1 (MCYG_03290), serine/threonine-protein kinase chk1 (VDBG_03742)

Other aliases include:

CHK1, Chk1, rad27, C85740, CHEK1, LOC398191, chk1, chek1

On the protein level the following designations are being used for antigen Checkpoint Kinase 1:

checkpoint kinase 1 – Checkpoint, S. pombe, homolog of, 1 – serine/threonine-protein kinase Chk1 – rad27 homolog – checkpoint kinase 1 homolog – CHK1 checkpoint homolog – integral membrane protein 1 – Serine/threonine-protein kinase Chk1 – serine/threonine-protein kinase chk1

Checkpoint Kinase 1 fulfills a number of functions:

ATP binding – nucleotide binding – protein binding – protein kinase binding – protein serine/threonine kinase activity – transferase activity – kinase activity – protein kinase activity – oligosaccharyl transferase activity

Checkpoint Kinase 1 is relevant to the following processes:

DNA damage checkpoint – DNA repair – DNA replication – G2/M transition of mitotic cell cycle – cell cycle – gamete generation – negative regulation of cell proliferation – protein amino acid phosphorylation – reciprocal meiotic recombination – regulation of cyclin-dependent protein kinase activity – response to DNA damage stimulus – DNA damage induced protein phosphorylation – G2/M transition DNA damage checkpoint – phosphorylation – regulation of S phase – cellular response to caffeine – cellular response to organic substance – protein amino acid N-linked glycosylation via asparagine – protein amino acid glycosylation

Locations for Checkpoint Kinase 1:

condensed nuclear chromosome – cytoplasm – nucleoplasm – nucleus – replication fork – cytoskeleton – cellular_component – chromosome, telomeric region – microtubule organizing center – membrane – membrane fraction – oligosaccharyltransferase complex

Source: NCBI Entrez Gene, Gene Ontology

anti-Checkpoint Kinase 1 (CHEK1) antibody (ABIN387806) cited in Oncogene

» More publications