The following gene names and symbols are associated with antigen Checkpoint Kinase 2 across different species:

CHK2 checkpoint homolog (S. pombe) (CHEK2), serine/threonine-protein kinase chk2 (MCYG_07308)

Other aliases include:

CDS1, CHK2, LFS2, RAD53, HuCds1, PP1425

On the protein level the following designations are being used for antigen Checkpoint Kinase 2:

protein kinase CHK2 – OTTHUMP00000199044 – OTTHUMP00000199045 – OTTHUMP00000199116 – checkpoint-like protein CHK2 – serine/threonine-protein kinase CHK2 – serine/threonine-protein kinase chk2

Checkpoint Kinase 2 fulfills a number of functions:

ATP binding – magnesium ion binding – nucleotide binding – protein binding – protein serine/threonine kinase activity – transferase activity

Checkpoint Kinase 2 is relevant to the following processes:

DNA damage checkpoint – DNA damage response, signal transduction resulting in induction of apoptosis – cell cycle – protein amino acid phosphorylation – response to DNA damage stimulus

Locations for Checkpoint Kinase 2:

PML body – nucleus

Source: NCBI Entrez Gene, Gene Ontology

anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN309588) cited in Histology and histopathology

anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN137205) cited in Cancer letters

anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN137205) cited in Proceedings of the National Academy of Sciences of the United States of America

anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN137205) cited in The Journal of biological chemistry

anti-Checkpoint Kinase 2 (CHEK2) antibody (ABIN137205) cited in Nature cell biology

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