The following gene names and symbols are associated with antigen Coagulation Factor II (thrombin) Receptor across different species:

coagulation factor II (thrombin) receptor (F2R), coagulation factor II (thrombin) receptor (F2r)

Other aliases include:

TR, HTR, CF2R, PAR1, PAR-1, Par1, TRGPC, MGC93622

On the protein level the following designations are being used for antigen Coagulation Factor II (thrombin) Receptor:

coagulation factor II receptor – thrombin receptor – protease-activated receptor 1 – proteinase-activated receptor 1 – PAR-1 – Thrombin receptor

Coagulation Factor II (thrombin) Receptor fulfills a number of functions:

G-protein coupled receptor activity – receptor activity – receptor binding – thrombin receptor activity – protein binding

Coagulation Factor II (thrombin) Receptor is relevant to the following processes:

G-protein coupled receptor protein signaling pathway – STAT protein nuclear translocation – activation of caspase activity – anatomical structure morphogenesis – connective tissue replacement during inflammatory response – negative regulation of cell proliferation – platelet activation – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of JAK-STAT cascade – positive regulation of MAPKKK cascade – positive regulation of blood coagulation – positive regulation of cell migration – positive regulation of collagen biosynthetic process – positive regulation of transcription, DNA-dependent – release of sequestered calcium ion into cytosol – response to wounding – signal transduction – tyrosine phosphorylation of STAT protein – activation of MAPKK activity – activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway – blood coagulation – connective tissue replacement involved in inflammatory response wound healing – death – elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger – establishment of synaptic specificity at neuromuscular junction – homeostasis of number of cells within a tissue – inflammatory response – negative regulation of neuron apoptosis – positive regulation of calcium ion transport – positive regulation of caspase activity – positive regulation of cell proliferation – positive regulation of phosphoinositide 3-kinase cascade – positive regulation of release of sequestered calcium ion into cytosol – positive regulation of smooth muscle contraction – positive regulation of vasoconstriction – regulation of blood coagulation – regulation of interleukin-1 beta production – regulation of sensory perception of pain – response to lipopolysaccharide – thrombin receptor signaling pathway

Locations for Coagulation Factor II (thrombin) Receptor:

Golgi apparatus – caveola – extracellular region – integral to plasma membrane – plasma membrane – platelet dense tubular network – integral to membrane – neuromuscular junction – postsynaptic membrane

Source: NCBI Entrez Gene, Gene Ontology