The following gene names and symbols are associated with antigen Cytokeratin 8 across different species:

keratin 8 (KRT8), keratin 18 (KRT18)

Other aliases include:

K8, KO, CK8, CYK8, K2C8, CARD2, K18, CYK18

On the protein level the following designations are being used for antigen Cytokeratin 8:

keratin 8 – cytokeratin 8 – keratin, type II cytoskeletal 8 – keratin 18 – cytokeratin 18 – cell proliferation-inducing protein 46

Cytokeratin 8 fulfills a number of functions:

protein binding – structural molecule activity

Cytokeratin 8 is relevant to the following processes:

apoptosis – cytoskeleton organization – interspecies interaction between organisms – response to other organism – tumor necrosis factor-mediated signaling pathway – Golgi to plasma membrane CFTR protein transport – anatomical structure morphogenesis – cell cycle – negative regulation of apoptosis

Locations for Cytokeratin 8:

Z disc – cytoplasm – keratin filament – sarcolemma – centriolar satellite – microtubule organizing center – perinuclear region of cytoplasm

Source: NCBI Entrez Gene, Gene Ontology