The following gene names and symbols are associated with antigen Elastase, Neutrophil Expressed across different species:

elastase, neutrophil expressed (ELANE), elastase, neutrophil expressed (Elane), elastase 2, neutrophil (ela2)

Other aliases include:

GE, NE, HLE, HNE, ELA2, PMN-E, Ela2, F430011M15Rik, ELANE, ela2, MGC89201, MGC157260

On the protein level the following designations are being used for antigen Elastase, Neutrophil Expressed:

neutrophil elastase – medullasin – leukocyte elastase – elastase 2, neutrophil – polymorphonuclear elastase – bone marrow serine protease – granulocyte-derived elastase – elastase-2 – pancreatic elastase II – serine protease – elastase, neutrophil expressed

Elastase, Neutrophil Expressed fulfills a number of functions:

bacterial binding – cytokine binding – peptidase activity – serine-type endopeptidase activity – catalytic activity – heparin binding – hydrolase activity – serine-type peptidase activity – endopeptidase activity – molecular_function – protein binding

Elastase, Neutrophil Expressed is relevant to the following processes:

cellular calcium ion homeostasis – leukocyte migration – negative regulation of chemokine biosynthetic process – negative regulation of chemotaxis – negative regulation of inflammatory response – negative regulation of interleukin-8 biosynthetic process – phagocytosis – positive regulation of MAP kinase activity – positive regulation of interleukin-8 biosynthetic process – positive regulation of smooth muscle cell proliferation – proteolysis – response to UV – acute inflammatory response to antigenic stimulus – defense response to fungus – metabolic process – negative regulation of growth of symbiont in host – neutrophil mediated killing of fungus – positive regulation of immune response – response to lipopolysaccharide – response to yeast – biological_process

Locations for Elastase, Neutrophil Expressed:

cell surface – extracellular region – cytoplasm – stored secretory granule – cellular_component

Source: NCBI Entrez Gene, Gene Ontology