The following gene names and symbols are associated with antigen Elastase 2, Neutrophil across different species:

elastase, neutrophil expressed (ELANE)

Other aliases include:

GE, NE, HLE, HNE, ELA2, PMN-E

On the protein level the following designations are being used for antigen Elastase 2, Neutrophil:

neutrophil elastase – medullasin – leukocyte elastase – elastase 2, neutrophil – polymorphonuclear elastase – bone marrow serine protease – granulocyte-derived elastase

Elastase 2, Neutrophil fulfills a number of functions:

bacterial binding – cytokine binding – peptidase activity – serine-type endopeptidase activity

Elastase 2, Neutrophil is relevant to the following processes:

cellular calcium ion homeostasis – leukocyte migration – negative regulation of chemokine biosynthetic process – negative regulation of chemotaxis – negative regulation of inflammatory response – negative regulation of interleukin-8 biosynthetic process – phagocytosis – positive regulation of MAP kinase activity – positive regulation of interleukin-8 biosynthetic process – positive regulation of smooth muscle cell proliferation – proteolysis – response to UV

Locations for Elastase 2, Neutrophil:

cell surface – extracellular region

Source: NCBI Entrez Gene, Gene Ontology