The following gene names and symbols are associated with antigen Endoglin across different species:

endoglin (ENG), endoglin (Eng), endoglin (LOC100226246), endoglin (LOC100357448)

Other aliases include:

END, ORW, HHT1, ORW1, CD105, FLJ41744, AI528660, AI662476, S-endoglin, Eng, MGC124909, ENG, MGC137842, DKFZp469D0419

On the protein level the following designations are being used for antigen Endoglin:

endoglin – CD105 antigen – OTTMUSP00000012838 – OTTMUSP00000012839 – transmembrane glycoprotein – cell surface MJ7/18 antigen – endoglin (Osler-Rendu-Weber syndrome 1) – endoglin-like

Endoglin fulfills a number of functions:

activin binding – galactose binding – glycosaminoglycan binding – protein binding – protein homodimerization activity – transforming growth factor beta binding – transforming growth factor beta receptor, cytoplasmic mediator activity – transmembrane receptor activity – type I transforming growth factor beta receptor binding – type II transforming growth factor beta receptor binding – binding – transforming growth factor beta receptor activity

Endoglin is relevant to the following processes:

artery morphogenesis – cell adhesion – central nervous system vasculogenesis – chronological cell aging – heart development – heart looping – negative regulation of protein amino acid autophosphorylation – patterning of blood vessels – positive regulation of BMP signaling pathway – positive regulation of pathway-restricted SMAD protein phosphorylation – regulation of transcription – regulation of transforming growth factor beta receptor signaling pathway – smooth muscle tissue development – venous blood vessel morphogenesis – angiogenesis – transforming growth factor beta receptor signaling pathway – vasculogenesis – biological_process

Locations for Endoglin:

external side of plasma membrane – extracellular space – integral to membrane – membrane – membrane fraction – transforming growth factor beta receptor complex – cell surface

Source: NCBI Entrez Gene, Gene Ontology