The following gene names and symbols are associated with antigen Endothelial PAS Domain Protein 1 across different species:

endothelial PAS domain protein 1 (EPAS1), endothelial PAS domain protein 1 (epas1)

Other aliases include:

HLF, MOP2, ECYT4, HIF2A, PASD2, bHLHe73, EPAS1, wu:fq36f01, EPAS-1

On the protein level the following designations are being used for antigen Endothelial PAS Domain Protein 1:

endothelial PAS domain protein 1 – HIF-1alpha-like factor – endothelial PAS domain-containing protein 1 – hif-2a – hypoxia inducible factor 2 alpha – HIF-2alpha – hypoxia-inducible factor 2 alpha – endothelial PAS domain-containing protein 1-like

Endothelial PAS Domain Protein 1 fulfills a number of functions:

RNA polymerase II transcription factor activity, enhancer binding – histone acetyltransferase binding – protein heterodimerization activity – sequence-specific DNA binding – signal transducer activity – transcription coactivator activity – transcription factor binding – sequence-specific DNA binding transcription factor activity – transcription factor activity – DNA binding – transcription regulator activity

Endothelial PAS Domain Protein 1 is relevant to the following processes:

angiogenesis – blood vessel remodeling – cell differentiation – cell maturation – embryonic placenta development – erythrocyte differentiation – hemopoiesis – lung development – mitochondrion organization – multicellular organismal development – norepinephrine metabolic process – positive regulation of transcription from RNA polymerase II promoter – regulation of heart rate – regulation of transcription from RNA polymerase II promoter in response to oxidative stress – regulation of transcription, DNA-dependent – response to hypoxia – response to oxidative stress – signal transduction – surfactant homeostasis – visual perception – regulation of transcription – transcription

Locations for Endothelial PAS Domain Protein 1:

cytoplasm – nucleus – transcription factor complex

Source: NCBI Entrez Gene, Gene Ontology