The following gene names and symbols are associated with antigen Endothelin 1 across different species:

endothelin 1 (EDN1), endothelin-1 (ET-1), endothelin 1 (edn1), endothelin 1 (Edn1), endothelin 1 (et-1)

Other aliases include:

ET1, HDLCQ7, EDN1, EDN, ET-1, Edn1, et1, et-1, preproET, Et1, fb14d01, wu:fb14d01, PPET1, PPET-1

On the protein level the following designations are being used for antigen Endothelin 1:

endothelin 1 – endothelin-1 – PPET1 – preproendothelin – preproendothelin-1 – ET-1 – suc – sucker – gene for endothelin – preproendothelin 1

Endothelin 1 fulfills a number of functions:

endothelin A receptor binding – endothelin B receptor binding – hormone activity – protein binding – receptor binding

Endothelin 1 is relevant to the following processes:

activation of phospholipase D activity by G-protein coupled receptor protein signaling pathway – activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway – artery smooth muscle contraction – blood vessel morphogenesis – calcium-mediated signaling – cartilage development – cell-cell signaling – diuresis – dorsal/ventral pattern formation – elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating) – glucose transport – heart development – in utero embryonic development – inositol phosphate-mediated signaling – leukocyte activation – membrane depolarization – middle ear morphogenesis – natriuresis – negative regulation of blood coagulation – negative regulation of cAMP biosynthetic process – negative regulation of hormone secretion – negative regulation of nitric-oxide synthase biosynthetic process – neural crest cell development – neutrophil chemotaxis – nitric oxide transport – patterning of blood vessels – peptide hormone secretion – phosphoinositide 3-kinase cascade – positive regulation of JUN kinase activity – positive regulation of cardiac muscle hypertrophy – positive regulation of cell size – positive regulation of endothelial cell migration – positive regulation of heart rate – positive regulation of hormone secretion – positive regulation of mitosis – positive regulation of nitric oxide biosynthetic process – positive regulation of prostaglandin-endoperoxidase synthase activity – positive regulation of sarcomere organization – positive regulation of smooth muscle cell proliferation – positive regulation of smooth muscle contraction – prostaglandin biosynthetic process – protein kinase C deactivation – regulation of blood pressure – regulation of pH – regulation of systemic arterial blood pressure by endothelin – regulation of vasoconstriction – respiratory gaseous exchange – response to hypoxia – rhythmic excitation – vein smooth muscle contraction – G-protein coupled receptor protein signaling pathway – body fluid secretion – elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger – intracellular protein kinase cascade – positive regulation of cell proliferation – regulation of blood vessel size – skeletal system development – vasoconstriction – cell surface receptor linked signaling pathway – elevation of cytosolic calcium ion concentration – positive regulation of MAP kinase activity – positive regulation of cell migration – embryonic viscerocranium morphogenesis

Locations for Endothelin 1:

cytoplasm – extracellular region – extracellular space

Source: NCBI Entrez Gene, Gene Ontology