The following gene names and symbols are associated with antigen Endothelin 2 across different species:

endothelin 2 (EDN2), endothelin 2 (Edn2), si:ch211-202b2.2 (si:ch211-202b2.2)

Other aliases include:

ET2, PPET2, VIC, Et2, ET-2, EDN2, edn2

On the protein level the following designations are being used for antigen Endothelin 2:

endothelin-2 – ET-2 – preproendothelin 2 – preproendothelin-2 – PPET2 – OTTMUSP00000009155 – vasoactive intestinal contractor peptide – VIC – RNEDN2S01 – Endothelin isopeptide 2 – vasoactive intestinal contractor – endothelin 2 – si:ch211-202b2.2

Endothelin 2 fulfills a number of functions:

endothelin B receptor binding – hormone activity

Endothelin 2 is relevant to the following processes:

activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway – artery smooth muscle contraction – calcium-mediated signaling – cell surface receptor linked signaling pathway – cytokine-mediated signaling pathway – elevation of cytosolic calcium ion concentration – hormonal regulation of the force of heart contraction – inositol phosphate-mediated signaling – macrophage activation – macrophage chemotaxis – negative regulation of hormone secretion – neutrophil chemotaxis – ovarian follicle rupture – positive regulation of cell proliferation – positive regulation of heart rate – positive regulation of hormone secretion – positive regulation of leukocyte chemotaxis – positive regulation of prostaglandin-endoperoxidase synthase activity – positive regulation of smooth muscle contraction – positive regulation of the force of heart contraction by chemical signal – prostaglandin biosynthetic process – regulation of blood pressure – regulation of systemic arterial blood pressure by endothelin – regulation of vasoconstriction – vasoconstriction – vein smooth muscle contraction – regulation of blood vessel size – positive regulation of prostaglandin-endoperoxide synthase activity

Locations for Endothelin 2:

extracellular region – extracellular space

Source: NCBI Entrez Gene, Gene Ontology