The following gene names and symbols are associated with antigen FADD across different species:

Fas (TNFRSF6)-associated via death domain (FADD)

Other aliases include:

GIG3, MORT1, MGC8528, FADD

On the protein level the following designations are being used for antigen FADD:

Fas-associated via death domain – growth-inhibiting gene 3 protein – mediator of receptor-induced toxicity – Fas-associating protein with death domain – Fas-associating death domain-containing protein – Fas (TNFRSF6)-associated via death domain

FADD fulfills a number of functions:

death receptor binding – identical protein binding – protein binding

FADD is relevant to the following processes:

activation of pro-apoptotic gene products – induction of apoptosis via death domain receptors – interspecies interaction between organisms – necrotic cell death – positive regulation of I-kappaB kinase/NF-kappaB cascade – regulation of apoptosis – signal transduction

Locations for FADD:

cytosol – death-inducing signaling complex

Source: NCBI Entrez Gene, Gene Ontology