The following gene names and symbols are associated with antigen PTK2 Protein Tyrosine Kinase 2 across different species:

PTK2 protein tyrosine kinase 2 (PTK2), PTK2 protein tyrosine kinase 2 (Ptk2), protein tyrosine kinase 2.1 (ptk2.1), focal adhesion kinase pp125FAK (Ptk2), PTK2 protein tyrosine kinase 2 (ptk2)

Other aliases include:

FAK, FADK, FAK1, pp125FAK, FRNK, Fadk, KIAA4203, mKIAA4203, fak, ptk2, fak1a, MGC66114, zgc:66114, wu:fa18c04, Ptk2, PTK2

On the protein level the following designations are being used for antigen PTK2 Protein Tyrosine Kinase 2:

PTK2 protein tyrosine kinase 2 – focal adhesion kinase 1 – focal adhesion kinase – protein tyrosine kinase 2.1 – protein-tyrosine kinase – focal adhesion kinase pp125FAK – FADK 1 – pp125FAK – protein tyrosine kinase 2 – protein-tyrosine kinase 2 – focal adhesion kinase-related nonkinase – focal adhesion kinase 1-like

PTK2 Protein Tyrosine Kinase 2 fulfills a number of functions:

ATP binding – SH2 domain binding – non-membrane spanning protein tyrosine kinase activity – nucleotide binding – protein binding – signal transducer activity – transferase activity – kinase activity – protein kinase activity – protein tyrosine kinase activity – integrin binding – phosphoinositide 3-kinase binding – protein complex binding

PTK2 Protein Tyrosine Kinase 2 is relevant to the following processes:

integrin-mediated signaling pathway – protein amino acid phosphorylation – signal complex assembly – angiogenesis – blood vessel development – cell motion – central nervous system neuron axonogenesis – endothelial cell migration – establishment of nucleus localization – extracellular matrix organization – microtubule cytoskeleton organization – negative regulation of axonogenesis – negative regulation of organ growth – negative regulation of synaptogenesis – neuron migration – protein amino acid autophosphorylation – vasculogenesis – cytoskeleton – JNK cascade – MAPKKK cascade – cellular chloride ion homeostasis – fat cell differentiation – negative regulation of apoptosis – negative regulation of cell migration – phosphorylation – positive regulation of cell adhesion – positive regulation of cell growth – positive regulation of cell migration – positive regulation of glial cell proliferation – positive regulation of phagocytosis – positive regulation of smooth muscle cell migration – positive regulation of smooth muscle cell proliferation – positive regulation of synaptic transmission – positive regulation of vasodilation – response to arsenic – response to drug – response to estradiol stimulus – response to glucose stimulus – response to mechanical stimulus – response to organic cyclic substance – response to organic nitrogen – response to organic substance

Locations for PTK2 Protein Tyrosine Kinase 2:

cell junction – cytoplasm – cytoskeleton – cytosol – focal adhesion – internal side of plasma membrane – plasma membrane – apical plasma membrane – lamellipodium – membrane – basolateral plasma membrane – intercalated disc – nuclear body – nucleolus – nucleus – sarcolemma

Source: NCBI Entrez Gene, Gene Ontology

6 products cited in Oncogene anti-Paxillin (PXN) (pTyr31) antibody (ABIN160690) , anti-Paxillin (PXN) (pTyr31) antibody (ABIN160691) , anti-Paxillin (PXN) (pTyr118) antibody (ABIN160692) , anti-PTK2 Protein Tyrosine Kinase 2 (PTK2) antibody (ABIN160738) , anti-PTK2 Protein Tyrosine Kinase 2 (PTK2) antibody (ABIN160739) , among others.

2 products cited in Proceedings of the National Academy of Sciences of the United States of America anti-PTK2 Protein Tyrosine Kinase 2 (PTK2) antibody (ABIN160738) , anti-PTK2 Protein Tyrosine Kinase 2 (PTK2) antibody (ABIN160739)

2 products cited in Proceedings of the National Academy of Sciences of the United States of America anti-PTK2 Protein Tyrosine Kinase 2 (PTK2) antibody (ABIN160738) , anti-PTK2 Protein Tyrosine Kinase 2 (PTK2) antibody (ABIN160739)

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