The following gene names and symbols are associated with antigen FK506 Binding Protein 1B, 12.6 KDa across different species:

FK506 binding protein 1B, 12.6 kDa (FKBP1B), FK506 binding protein 1b (Fkbp1b), FK506 binding protein 1B, 12.6 kDa (fkbp1b), FK506 binding protein 1A, 12kDa (FKBP1A), FK506 binding protein 1B, 12.6 kDa (LOC100230320)

Other aliases include:

OTK4, FKBP1L, PKBP1L, PPIase, FKBP12.6, MGC68829, FKBP1B, FKBP1A, DKFZp459K1429

On the protein level the following designations are being used for antigen FK506 Binding Protein 1B, 12.6 KDa:

FK506 binding protein 1B, 12.6 kDa – rotamase – calstabin 2 – immunophilin FKBP12.6 – FK506-binding protein 12.6 – FK506-binding protein 1-like – peptidyl-prolyl cis-trans isomerase – FK506 binding protein 12.6 – calstabin2 – FK506 binding protein 1A, 12kDa – FK506-binding protein 1A – PPIase 1B – Rotamase 1B – 12.6 kDa FKBP – Immunophilin FKBP12.6 – peptidyl-prolyl cis-trans isomerase 1B – peptidyl-prolyl cis-trans isomerase; PPIase

FK506 Binding Protein 1B, 12.6 KDa fulfills a number of functions:

FK506 binding – isomerase activity – peptidyl-prolyl cis-trans isomerase activity – receptor binding – ryanodine-sensitive calcium-release channel activity – protein binding – drug binding

FK506 Binding Protein 1B, 12.6 KDa is relevant to the following processes:

'de novo' protein folding – muscle contraction – negative regulation of heart rate – negative regulation of protein phosphatase type 2B activity – protein maturation by protein folding – protein refolding – regulation of calcium ion transport via store-operated calcium channel activity – regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion – regulation of ryanodine-sensitive calcium-release channel activity – response to redox state – T cell proliferation – elevation of cytosolic calcium ion concentration – insulin secretion – neuronal action potential propagation – protein folding – regulation of heart rate – release of sequestered calcium ion into cytosol – release of sequestered calcium ion into cytosol by sarcoplasmic reticulum – response to glucose stimulus – response to hydrogen peroxide – response to organic substance – response to vitamin E – smooth muscle contraction – cytokine-mediated signaling pathway – negative regulation of protein amino acid phosphorylation – response to caffeine

Locations for FK506 Binding Protein 1B, 12.6 KDa:

calcium channel complex – cytoplasm – cytosol – microsome – sarcoplasmic reticulum membrane – membrane fraction

Source: NCBI Entrez Gene, Gene Ontology