The following gene names and symbols are associated with antigen Heart and Neural Crest Derivatives Expressed 2 across different species:

heart and neural crest derivatives expressed 2 (HAND2), heart and neural crest derivatives expressed 2 (Hand2), heart and neural crest derivatives expressed 2 (hand2-A), heart and neural crest derivatives expressed 2 (hand2-b), heart and neural crest derivatives expressed 2 (hand2), heart and neural crest derivatives expressed 2 (LOC100218345)

Other aliases include:

Hed, dHand, DHAND2, Thing2, bHLHa26, FLJ16260, MGC125303, MGC125304, hand2-A, MGC154423, hand2-b, Hand2', HAND2, dHAND, hed, dhand, dhand2, thing2, xhand2, LOC100218345

On the protein level the following designations are being used for antigen Heart and Neural Crest Derivatives Expressed 2:

basic helix-loop-helix transcription factor HAND2 – heart and neural crest derivatives expressed 2 – dHand protein – heart and neural crest derivatives expressed transcript 2 – heart- and neural crest derivatives-expressed protein 2

Heart and Neural Crest Derivatives Expressed 2 fulfills a number of functions:

DNA binding – promoter binding – protein heterodimerization activity – protein homodimerization activity – transcription activator binding – transcription coactivator activity – transcription factor binding – protein binding – protein domain specific binding – transcription activator activity – transcription factor activity – transcription regulator activity

Heart and Neural Crest Derivatives Expressed 2 is relevant to the following processes:

adult heart development – angiogenesis – apoptosis – cell differentiation – heart looping – in utero embryonic development – multicellular organismal development – neural crest cell development – positive regulation of transcription from RNA polymerase II promoter – regulation of transcription, DNA-dependent – heart development – heart morphogenesis – regulation of transcription

Locations for Heart and Neural Crest Derivatives Expressed 2:

nucleus – transcription factor complex

Source: NCBI Entrez Gene, Gene Ontology