The following gene names and symbols are associated with antigen High-Mobility Group Box 2 across different species:

high-mobility group box 2 (HMGB2)

Other aliases include:

HMG2

On the protein level the following designations are being used for antigen High-Mobility Group Box 2:

high-mobility group box 2 – high-mobility group (nonhistone chromosomal) protein 2

High-Mobility Group Box 2 fulfills a number of functions:

DNA bending activity – double-stranded DNA binding – general transcriptional repressor activity – protein binding – single-stranded DNA binding – transcription factor activity

High-Mobility Group Box 2 is relevant to the following processes:

DNA repair – DNA replication – DNA unwinding during replication – base-excision repair, DNA ligation – chromatin organization – male gonad development – negative regulation of transcription – nucleosome assembly – phosphoinositide-mediated signaling – positive regulation of gene-specific transcription from RNA polymerase II promoter – regulation of transcription from RNA polymerase II promoter – response to steroid hormone stimulus – spermatogenesis

Locations for High-Mobility Group Box 2:

condensed chromosome – cytoplasm – nuclear chromosome – nucleolus – nucleoplasm – nucleus – perinuclear region of cytoplasm

Source: NCBI Entrez Gene, Gene Ontology