The following gene names and symbols are associated with antigen Histone Deacetylase 2 across different species:

histone deacetylase 2 (HDAC2), histone deacetylase 2 (Hdac2)

Other aliases include:

RPD3, YAF1, Yy1bp, mRPD3, D10Wsu179e

On the protein level the following designations are being used for antigen Histone Deacetylase 2:

histone deacetylase 2 – YY1-associated factor 1 – transcriptional regulator homolog RPD3 – HD2 – OTTMUSP00000022803 – YY1 transcription factor-binding protein – histone deacetylase-2

Histone Deacetylase 2 fulfills a number of functions:

enzyme binding – histone deacetylase activity – hydrolase activity – sequence-specific DNA binding – specific transcriptional repressor activity – transcription activator activity – transcription factor activity – transcription factor binding – heat shock protein binding – protein binding – sequence-specific DNA binding transcription factor activity – protein deacetylase activity

Histone Deacetylase 2 is relevant to the following processes:

chromatin remodeling – histone deacetylation – maintenance of chromatin silencing – negative regulation of MHC class II biosynthetic process – negative regulation of cell cycle – negative regulation of gene-specific transcription from RNA polymerase II promoter – negative regulation of transcription factor activity – positive regulation of cell proliferation – positive regulation of collagen biosynthetic process – positive regulation of gene-specific transcription from RNA polymerase II promoter – positive regulation of proteolysis – positive regulation of receptor biosynthetic process – regulation of transcription – chromatin modification – hippocampus development – negative regulation of neuron projection development – negative regulation of transcription – neuron differentiation – transcription – cellular response to heat – response to cocaine – response to drug

Locations for Histone Deacetylase 2:

NuRD complex – Sin3 complex – cytoplasm – heterochromatin – nucleus – replication fork – chromatin – ESC/E(Z) complex – histone deacetylase complex

Source: NCBI Entrez Gene, Gene Ontology