The following gene names and symbols are associated with antigen Holocarboxylase Synthetase across different species:

holocarboxylase synthetase (biotin-(proprionyl-Coenzyme A-carboxylase (ATP-hydrolysing)) ligase) (HLCS), biotin apo-protein ligase (birA), biotin apo-protein ligase (AFUA_2G09550), biotin apo-protein ligase (H16_B1756), biotin apo-protein ligase (BDBG_06963), Holocarboxylase synthetase (Hcs), holocarboxylase synthetase (Hcs), holocarboxylase synthetase (BPL1), holocarboxylase synthetase (LOC100282872), holocarboxylase synthetase (LOC100286155)

Other aliases include:

HCS, CG14670, DmelCG14670, NEST:bs27h05

On the protein level the following designations are being used for antigen Holocarboxylase Synthetase:

holocarboxylase synthetase – OTTHUMP00000109039 – biotin apo-protein ligase – CG14670-PA – Hcs-PA

Holocarboxylase Synthetase fulfills a number of functions:

ATP binding – biotin-[acetyl-CoA-carboxylase] ligase activity – biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity – biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity – biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity – ligase activity – nucleotide binding

Holocarboxylase Synthetase is relevant to the following processes:

protein modification process – response to heat

Locations for Holocarboxylase Synthetase:

cytoplasm – cytosol – mitochondrion – polytene chromosome

Source: NCBI Entrez Gene, Gene Ontology