The following gene names and symbols are associated with antigen Insulin Receptor across different species:

insulin receptor (INSR), insulin receptor (Insr), Insulin-like receptor (InR)

Other aliases include:

HHF5, CD220, IR, 4932439J01Rik, D630014A15Rik, DIHR, DILR, DIR, DIRH, DIRbeta, DInR, Dir-a, Dir-b, INR, Inr-alpha, Inr-beta, InsR, dInsR, er10, insulin/insulin-like growth factor receptor, l(3)05545, l(3)93Dj, l(3)er10, DmelCG18402, CG18402, INSR, ir-A, CTK-1, ir, NV14476

On the protein level the following designations are being used for antigen Insulin Receptor:

insulin receptor – Insulin-like receptor, isoform B – CG18402-PB – InR-PB – insulin-receptor – insulin receptor homolog – lethal(3)93Dj – Insulin-like receptor – Insulin-like receptor, isoform A – CG18402-PA – InR-PA – Insulin-like receptor, isoform C – CG18402-PC – InR-PC – Insulin-like receptor, isoform D – CG18402-PD – InR-PD – tyrosine kinase – insulin receptor tyrosine kinase – insulin receptor-like

Insulin Receptor fulfills a number of functions:

3-phosphoinositide-dependent protein kinase binding – ATP binding – GTP binding – PTB domain binding – SH2 domain binding – insulin binding – insulin receptor activity – insulin receptor substrate binding – insulin-like growth factor I binding – insulin-like growth factor II binding – insulin-like growth factor receptor binding – nucleotide binding – phosphoinositide 3-kinase binding – protein phosphatase binding – receptor activity – receptor signaling protein tyrosine kinase activity – transferase activity – kinase activity – protein binding – protein kinase activity – protein tyrosine kinase activity – transmembrane receptor protein tyrosine kinase activity – lipoic acid binding – protein complex binding – protein domain specific binding – protein kinase binding – cytokine receptor activity – insulin-like growth factor binding

Insulin Receptor is relevant to the following processes:

G-protein coupled receptor protein signaling pathway – activation of MAPK activity – activation of protein kinase B activity – carbohydrate metabolic process – glucose homeostasis – heart morphogenesis – insulin receptor signaling pathway – male sex determination – peptidyl-tyrosine phosphorylation – positive regulation of DNA replication – positive regulation of MAPKKK cascade – positive regulation of cell migration – positive regulation of cell proliferation – positive regulation of developmental growth – positive regulation of glucose import – positive regulation of glycogen biosynthetic process – positive regulation of glycolysis – positive regulation of mitosis – positive regulation of nitric oxide biosynthetic process – positive regulation of protein amino acid phosphorylation – positive regulation of protein kinase B signaling cascade – positive regulation of respiratory burst – protein amino acid autophosphorylation – protein heterotetramerization – regulation of embryonic development – regulation of gene-specific transcription – transformation of host cell by virus – exocrine pancreas development – organ morphogenesis – protein amino acid phosphorylation – transmembrane receptor protein tyrosine kinase signaling pathway – fat cell differentiation – negative regulation of gene expression – negative regulation of protein amino acid phosphorylation – negative regulation of transporter activity – positive regulation of glycoprotein biosynthetic process – regulation of hydrogen peroxide metabolic process – response to activity – response to estradiol stimulus – response to ethanol – response to glucocorticoid stimulus – response to hormone stimulus – response to insulin stimulus – response to manganese ion – response to nutrient levels – response to protein stimulus – response to testosterone stimulus – response to tumor necrosis factor – response to vitamin D – aging – axon guidance – cell growth – cellular response to DNA damage stimulus – determination of adult lifespan – developmental growth – dorsal closure – embryonic development – embryonic development via the syncytial blastoderm – germ-band shortening – germ-line stem-cell niche homeostasis – growth – imaginal disc growth – male germ-line stem cell division – positive regulation of cell growth – positive regulation of cell size – positive regulation of multicellular organism growth – positive regulation of organ growth – primary spermatocyte growth – regulation of cell proliferation – regulation of cell size – regulation of multicellular organism growth – regulation of organ growth – response to cocaine – response to nutrient – vitellogenesis – negative regulation of apoptosis

Locations for Insulin Receptor:

caveola – cytosol – endosome – endosome membrane – insulin receptor complex – microsome – plasma membrane – integral to membrane – membrane – nucleus – soluble fraction – synapse – cell-cell junction – integral to plasma membrane

Source: NCBI Entrez Gene, Gene Ontology