The following gene names and symbols are associated with antigen Insulin-Degrading Enzyme across different species:

insulin-degrading enzyme (IDE), insulin degrading enzyme (Ide), zgc:162603 (zgc:162603), insulin-degrading enzyme (CC1G_01115), insulin-degrading enzyme (Bm1_26615), insulin-degrading enzyme (PTRG_10875), insulin-degrading enzyme (SJAG_01430), insulin-degrading enzyme (EBI_21700), insulin-degrading enzyme (VDBG_06702), insulin-degrading enzyme (LOAG_08082), insulin-degrading enzyme (PGTG_04982), insulin-degrading enzyme (Tsp_00424)

Other aliases include:

FLJ35968, INSULYSIN, AA675336, AI507533, 1300012G03Rik, 4833415K22Rik, INSDEGM, IDE, ide, MGC162603

On the protein level the following designations are being used for antigen Insulin-Degrading Enzyme:

insulin-degrading enzyme – insulinase – insulin protease – Abeta-degrading protease – insulysin – insulin-degrading enzyme-like

Insulin-Degrading Enzyme fulfills a number of functions:

ATP binding – metal ion binding – metalloendopeptidase activity – nucleotide binding – peptidase activity – protein homodimerization activity – signal transducer activity – zinc ion binding – catalytic activity – hydrolase activity – metallopeptidase activity – ATPase activity – beta-endorphin binding – insulin binding – peptide hormone binding

Insulin-Degrading Enzyme is relevant to the following processes:

beta-amyloid metabolic process – bradykinin catabolic process – proteolysis – sex differentiation – signal transduction – cellular protein catabolic process – hormone catabolic process – negative regulation of proteolysis – peptide catabolic process – protein heterooligomerization – protein homotetramerization – proteolysis involved in cellular protein catabolic process

Locations for Insulin-Degrading Enzyme:

cytoplasm – extracellular space – peroxisome – soluble fraction – mitochondrion – cell surface – cytosol – cytosolic proteasome complex – nucleus – peroxisomal matrix – cellular_component

Source: NCBI Entrez Gene, Gene Ontology