The following gene names and symbols are associated with antigen Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide) across different species:

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL), integrin alpha L (Itgal)

Other aliases include:

CD11A, LFA-1, LFA1A, Cd11a, Ly-15, Ly-21, ITGAL, CD11a

On the protein level the following designations are being used for antigen Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide):

integrin alpha L – LFA-1 alpha – integrin gene promoter – lymphocyte function-associated antigen 1 – antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide – integrin alpha-L – LFA-1A – CD11A (p180) – OTTMUSP00000041057 – OTTMUSP00000041058 – OTTMUSP00000041059 – lymphocyte antigen 15 – CD11 antigen-like family member A – leukocyte adhesion glycoprotein LFA-1 alpha chain – leukocyte function-associated molecule 1 alpha chain – lymphocyte function associated antigen 1, alpha polypeptide – integrin LFA1 – lymphocyte function-associated antigen 1, alpha polypeptide

Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide) fulfills a number of functions:

calcium ion binding – cell adhesion molecule binding – magnesium ion binding – receptor activity – protein heterodimerization activity

Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide) is relevant to the following processes:

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell – cell adhesion – cell motion – heterophilic cell adhesion – inflammatory response – integrin-mediated signaling pathway – leukocyte adhesion – signal transduction – activated T cell proliferation – cell surface receptor linked signaling pathway – cell-cell adhesion – leukocyte cell-cell adhesion – positive regulation of T cell proliferation – positive regulation of calcium-mediated signaling – positive regulation of cell-cell adhesion – regulation of cell-cell adhesion

Locations for Integrin, alpha L (Antigen CD11A (p180), Lymphocyte Function-Associated Antigen 1; alpha Polypeptide):

integral to membrane – integrin complex – plasma membrane – cell surface – external side of plasma membrane – immunological synapse – membrane

Source: NCBI Entrez Gene, Gene Ontology