The following gene names and symbols are associated with antigen Integrin alpha 2 across different species:

integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) (ITGA2), integrin alpha 2 (Itga2)

Other aliases include:

BR, GPIa, CD49B, VLA-2, VLAA2, DX5

On the protein level the following designations are being used for antigen Integrin alpha 2:

integrin alpha 2 – platelet antigen Br – platelet glycoprotein Ia – platelet glycoprotein GPIa – very late activation protein 2 receptor, alpha-2 subunit – integrin alpha-2 – GPIa – collagen receptor – VLA-2 subunit alpha – VLA-2 receptor, alpha 2 subunit – CD49 antigen-like family member B – platelet membrane glycoprotein Ia

Integrin alpha 2 fulfills a number of functions:

calcium ion binding – collagen binding – identical protein binding – magnesium ion binding – receptor activity – integrin binding – laminin binding – protein complex binding – protein heterodimerization activity

Integrin alpha 2 is relevant to the following processes:

blood coagulation – cell adhesion – cell-matrix adhesion – integrin-mediated signaling pathway – interspecies interaction between organisms – organ morphogenesis – detection of mechanical stimulus involved in sensory perception of pain – establishment of protein localization – hypotonic response – positive regulation of DNA binding – positive regulation of alkaline phosphatase activity – positive regulation of cell adhesion – positive regulation of cell projection organization – positive regulation of collagen binding – positive regulation of collagen biosynthetic process – positive regulation of epithelial cell migration – positive regulation of inflammatory response – positive regulation of leukocyte migration – positive regulation of phagocytosis, engulfment – positive regulation of positive chemotaxis – positive regulation of smooth muscle cell migration – positive regulation of smooth muscle cell proliferation – positive regulation of smooth muscle contraction – positive regulation of translation – positive regulation of transmission of nerve impulse – skin morphogenesis – tissue homeostasis

Locations for Integrin alpha 2:

external side of plasma membrane – integral to membrane – integrin complex – plasma membrane – axon – axon terminus – cell outer membrane – cell projection – cell surface – focal adhesion – membrane – nucleus – perinuclear region of cytoplasm

Source: NCBI Entrez Gene, Gene Ontology