The following gene names and symbols are associated with antigen Integrin alpha-L across different species:

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) (ITGAL)

Other aliases include:

CD11A, LFA-1, LFA1A

On the protein level the following designations are being used for antigen Integrin alpha-L:

integrin alpha L – LFA-1 alpha – integrin gene promoter – lymphocyte function-associated antigen 1 – antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide

Integrin alpha-L fulfills a number of functions:

calcium ion binding – cell adhesion molecule binding – magnesium ion binding – receptor activity

Integrin alpha-L is relevant to the following processes:

T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell – cell adhesion – cell motion – heterophilic cell adhesion – inflammatory response – integrin-mediated signaling pathway – leukocyte adhesion – signal transduction

Locations for Integrin alpha-L:

integral to membrane – integrin complex – plasma membrane

Source: NCBI Entrez Gene, Gene Ontology