The following gene names and symbols are associated with antigen Interleukin-1 Receptor-Associated Kinase 1 across different species:

interleukin-1 receptor-associated kinase 1 (IRAK1), interleukin-1 receptor-associated kinase 1 (irak1), interleukin-1 receptor-associated kinase 1 (Irak1)

Other aliases include:

IRAK, pelle, IRAK1, Plpk, mPLK, IRAK-1, Il1rak, IRAK1-S, AA408924, RGD1563841

On the protein level the following designations are being used for antigen Interleukin-1 Receptor-Associated Kinase 1:

interleukin-1 receptor-associated kinase 1 – Pelle homolog – interleukin receptor associated kinase 1 – OTTMUSP00000019684 – OTTMUSP00000020303 – OTTMUSP00000020306 – pelle-like protein kinase – interleukin-1 receptor-associated kinase-1

Interleukin-1 Receptor-Associated Kinase 1 fulfills a number of functions:

ATP binding – NF-kappaB-inducing kinase activity – magnesium ion binding – nucleotide binding – protein heterodimerization activity – protein homodimerization activity – protein serine/threonine kinase activity – transcription activator activity – transferase activity – kinase activity – protein binding – protein kinase activity – receptor activity – interleukin-1 receptor binding – identical protein binding

Interleukin-1 Receptor-Associated Kinase 1 is relevant to the following processes:

MyD88-dependent toll-like receptor signaling pathway – activation of NF-kappaB-inducing kinase activity – anti-apoptosis – interleukin-1-mediated signaling pathway – lipopolysaccharide-mediated signaling pathway – negative regulation of NF-kappaB transcription factor activity – positive regulation of NF-kappaB transcription factor activity – positive regulation of transcription – protein amino acid autophosphorylation – protein oligomerization – regulation of cytokine-mediated signaling pathway – response to interleukin-1 – response to lipopolysaccharide – signal transduction – toll-like receptor 2 signaling pathway – transmembrane receptor protein serine/threonine kinase signaling pathway – protein amino acid phosphorylation – JNK cascade – cytokine-mediated signaling pathway – innate immune response – negative regulation of gene-specific transcription – positive regulation of JUN kinase activity – positive regulation of MAP kinase activity – positive regulation of smooth muscle cell proliferation – positive regulation of transcription from RNA polymerase II promoter – regulation of cholesterol efflux – response to molecule of bacterial origin – response to peptidoglycan – toll-like receptor 4 signaling pathway – I-kappaB kinase/NF-kappaB cascade

Locations for Interleukin-1 Receptor-Associated Kinase 1:

cytosol – interleukin-1 receptor complex – membrane fraction – soluble fraction

Source: NCBI Entrez Gene, Gene Ontology