The following gene names and symbols are associated with antigen Lymphotoxin-alpha across different species:

lymphotoxin alpha (TNF superfamily, member 1) (LTA)

Other aliases include:

LT, TNFB, TNFSF1

On the protein level the following designations are being used for antigen Lymphotoxin-alpha:

lymphotoxin alpha – OTTHUMP00000165897 – tumor necrosis factor beta

Lymphotoxin-alpha fulfills a number of functions:

cytokine activity – tumor necrosis factor receptor binding

Lymphotoxin-alpha is relevant to the following processes:

apoptosis – calcium-mediated signaling – cell activation – cell-cell signaling – humoral immune response – induction of apoptosis – lymph node development – negative regulation of L-glutamate transport – negative regulation of cell proliferation – negative regulation of glucose import – positive regulation of I-kappaB kinase/NF-kappaB cascade – positive regulation of mitosis – positive regulation of neuron apoptosis – positive regulation of protein transport – positive regulation of synaptic transmission – response to mechanical stimulus – signal transduction

Locations for Lymphotoxin-alpha:

extracellular region – extracellular space – integral to membrane – membrane

Source: NCBI Entrez Gene, Gene Ontology