The following gene names and symbols are associated with antigen MAP-Kinase Activating Death Domain across different species:

MAP-kinase activating death domain (MADD), MAP-kinase activating death domain (Madd), MAP-kinase activating death domain (madd)

Other aliases include:

DENN, IG20, RAB3GEP, FLJ35600, FLJ36300, KIAA0358, 9630059K23Rik, MADD, MGC145371

On the protein level the following designations are being used for antigen MAP-Kinase Activating Death Domain:

MAP-kinase activating death domain-containing protein – OTTHUMP00000197132 – OTTHUMP00000197133 – OTTHUMP00000197138 – OTTHUMP00000197139 – Rab3 GDP/GTP exchange factor – insulinoma-glucagonoma protein 20 – differentially expressed in normal and neoplastic cells – MAP kinase-activating death domain protein – rab3 GDP/GTP exchange factor – Rab3 GDP/GTP exchange protein – Rab3 GEP – OTTMUSP00000015273 – OTTMUSP00000015274 – OTTMUSP00000015275 – OTTMUSP00000015276 – OTTMUSP00000015279 – OTTMUSP00000015280 – OTTMUSP00000015281 – OTTMUSP00000015282 – OTTMUSP00000015304 – MAP-kinase activating death domain – MAP kinase-activating death domain protein-like

MAP-Kinase Activating Death Domain fulfills a number of functions:

Rab guanyl-nucleotide exchange factor activity – death receptor binding – guanyl-nucleotide exchange factor activity – protein binding – protein kinase activator activity – kinase activity

MAP-Kinase Activating Death Domain is relevant to the following processes:

activation of MAPK activity – cell surface receptor linked signal transduction – regulation of apoptosis – regulation of cell cycle – apoptosis

Locations for MAP-Kinase Activating Death Domain:

cytoplasm – integral to membrane – plasma membrane – membrane

Source: NCBI Entrez Gene, Gene Ontology