The following gene names and symbols are associated with antigen Matrix Metalloproteinase 2 across different species:

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (MMP2), matrix metallopeptidase 2 (Mmp2), Matrix metalloproteinase 2 (Mmp2), matrix metalloproteinase 2 (mmp2), matrix metalloproteinase-2 (mmp-2), matrix metalloproteinase 2 (Mmp-2), matrix metalloproteinase-2 (LOC100135793)

Other aliases include:

CLG4, MONA, CLG4A, TBE-1, MMP-II, GelA, Clg4a, MMP-2, 2-MMP, Dm2-MMP, MMP2, anon-WO0118547.84, dm-2MMP, l(2)02353, DmelCG1794, CG1794, fa99h12, fk89d01, wu:fa99h12, wu:fk89d01, mmp-2, fgmmp-2, Mmp-2, LOC100135793

On the protein level the following designations are being used for antigen Matrix Metalloproteinase 2:

matrix metalloproteinase 2 – collagenase type IV-A – neutrophil gelatinase – matrix metalloproteinase-II – 72 kDa type IV collagenase – gelatinase A – 72kD gelatinase – 72kDa gelatinase – 72 kDa gelatinase – 72kD type IV collagenase – 72kDa type IV collagenase – matrix metalloproteinase-2 – matrix metalloproteinase 2, isoform A – CG1794-PA – Mmp2-PA – matrix metalloproteinase 2, isoform B – CG1794-PB – Mmp2-PB – MMP-2 – matrix metalloproteinase 2 (72 KDa type IV collagenase) – Gelatinase A – matrix metalloproteinase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) – matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Matrix Metalloproteinase 2 fulfills a number of functions:

calcium ion binding – metalloendopeptidase activity – peptidase activity – protein binding – zinc ion binding – fibronectin binding – hydrolase activity – metal ion binding – metallopeptidase activity

Matrix Metalloproteinase 2 is relevant to the following processes:

blood vessel maturation – bone trabecula formation – collagen catabolic process – face morphogenesis – intramembranous ossification – metabolic process – proteolysis – response to hypoxia – angiogenesis – axon regeneration in the peripheral nervous system – cell migration – cellular response to estradiol stimulus – negative regulation of cell adhesion – negative regulation of vasoconstriction – ovarian follicle development – positive regulation of apoptosis – prostate gland epithelium morphogenesis – response to drug – response to estrogen stimulus – response to hydrogen peroxide – response to mechanical stimulus – response to oxidative stress – skeletal system morphogenesis – tissue remodeling – basement membrane disassembly – imaginal disc eversion – imaginal disc fusion, thorax closure – oogenesis – aging – anatomical structure regression – cell growth – cellular response to cytokine stimulus – cellular response to interleukin-1 – female pregnancy – ovulation from ovarian follicle – parturition – response to activity – response to cytokine stimulus – response to electrical stimulus – response to nicotine – response to radiation

Locations for Matrix Metalloproteinase 2:

extracellular region – extracellular space – intracellular membrane-bounded organelle – plasma membrane – proteinaceous extracellular matrix – sarcomere – cytoplasm – extracellular matrix – membrane – nucleus – dendrite

Source: NCBI Entrez Gene, Gene Ontology

2 products cited in Rheumatology international Matrix Metallopeptidase 13 (Collagenase 3) (MMP13) ELISA Kit (ABIN365412) , Matrix Metalloproteinase 2 (MMP2) ELISA Kit (ABIN411328)

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