The following gene names and symbols are associated with antigen Minichromosome Maintenance Complex Component 7 across different species:

minichromosome maintenance complex component 7 (MCM7), Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase (MCM7), hypothetical protein (CDC47), minichromosome maintenance complex component 7 (Mcm7), minichromosome maintenance complex component 2 (MCM2)

Other aliases include:

MCM2, CDC47, HsMcm7, P85MCM, P1CDC47, PNAS-146, CDABP0042, P1.1-MCM3, MGC93853, MCM7

On the protein level the following designations are being used for antigen Minichromosome Maintenance Complex Component 7:

minichromosome maintenance complex component 7 – homolog of S. cerevisiae Cdc47 – DNA replication licensing factor MCM7 – minichromosome maintenance deficient 7 – MCM7 minichromosome maintenance deficient 7 – Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase – Mcm7p – hypothetical protein – minichromosome maintenance protein 7 – minichromosome maintenance complex component 2 – minichromosome maintenance protein 2 – DNA replication licensing factor MCM7-like – DNA replication licensing factor MCM2-like

Minichromosome Maintenance Complex Component 7 fulfills a number of functions:

ATP binding – DNA binding – DNA helicase activity – nucleoside-triphosphatase activity – nucleotide binding – protein binding – single-stranded DNA binding – ATP-dependent 3'-5' DNA helicase activity – DNA replication origin binding – chromatin binding – four-way junction helicase activity – single-stranded DNA-dependent ATPase activity – transcription cofactor activity – DNA-dependent ATPase activity

Minichromosome Maintenance Complex Component 7 is relevant to the following processes:

DNA replication – DNA replication initiation – DNA unwinding during replication – cell cycle – cell proliferation – regulation of phosphorylation – regulation of transcription – response to DNA damage stimulus – DNA strand elongation involved in DNA replication – DNA unwinding involved in replication – DNA-dependent DNA replication initiation – S phase of mitotic cell cycle – chromatin silencing at silent mating-type cassette – chromatin silencing at telomere – double-strand break repair via break-induced replication – pre-replicative complex assembly – protein complex assembly – regulation of transcription from RNA polymerase II promoter – transcription – cellular response to epidermal growth factor stimulus – cellular response to organic substance – regulation of transcription, DNA-dependent – response to drug

Locations for Minichromosome Maintenance Complex Component 7:

MCM complex – chromatin – cytoplasm – nucleoplasm – nucleus – DNA replication preinitiation complex – pre-replicative complex – replication fork protection complex – cytosol

Source: NCBI Entrez Gene, Gene Ontology