The following gene names and symbols are associated with antigen Mitogen-Activated Protein Kinase Kinase Kinase 5 across different species:

mitogen-activated protein kinase kinase kinase 5 (MAP3K5), mitogen-activated protein kinase kinase kinase 5 (Map3k5), mitogen-activated protein kinase kinase kinase 5 (MAPKKK5)

Other aliases include:

ASK1, MEKK5, MAPKKK5, MAP3K5, Ask1, mitogen-activated protein kinase kinase kinase 5, MUD21.11, MUD21_11

On the protein level the following designations are being used for antigen Mitogen-Activated Protein Kinase Kinase Kinase 5:

mitogen-activated protein kinase kinase kinase 5 – MAP/ERK kinase kinase 5 – MAPK/ERK kinase kinase 5 – apoptosis signal regulating kinase 1

Mitogen-Activated Protein Kinase Kinase Kinase 5 fulfills a number of functions:

ATP binding – MAP kinase kinase kinase activity – caspase activator activity – magnesium ion binding – nucleotide binding – protein homodimerization activity – protein serine/threonine kinase activity – transferase activity – JUN kinase kinase kinase activity – mitogen-activated protein kinase kinase binding – protein heterodimerization activity – kinase activity

Mitogen-Activated Protein Kinase Kinase Kinase 5 is relevant to the following processes:

MAPKKK cascade – activation of JUN kinase activity – apoptosis – induction of apoptosis by extracellular signals – interspecies interaction between organisms – protein amino acid phosphorylation – activation of JNKK activity – protein amino acid autophosphorylation – protein heterooligomerization – protein autophosphorylation

Locations for Mitogen-Activated Protein Kinase Kinase Kinase 5:

cell cortex – cytoplasm – nucleus – plasma membrane

Source: NCBI Entrez Gene, Gene Ontology