The following gene names and symbols are associated with antigen Mitogen-Activated Protein Kinase Kinase Kinase 8 across different species:

mitogen-activated protein kinase kinase kinase 8 (MAP3K8), mitogen-activated protein kinase kinase kinase 8 (Map3k8), mitogen-activated protein kinase kinase kinase 8 (map3k8)

Other aliases include:

COT, EST, ESTF, TPL2, MEKK8, Tpl-2, c-COT, FLJ10486, Cot, Est, Estf, Tpl2, Cot/Tpl2, D17TPL2, MAP3K8, MGC159463

On the protein level the following designations are being used for antigen Mitogen-Activated Protein Kinase Kinase Kinase 8:

mitogen-activated protein kinase kinase kinase 8 – OTTHUMP00000019392 – OTTHUMP00000019393 – tumor progression locus-2 – Ewing sarcoma transformant – Cancer Osaka thyroid oncogene – cot (cancer Osaka thyroid) oncogene – proto-oncogene serine/threoine protein kinase – proto-oncogene c-Cot – tumor progression locus 2 – cancer Osaka thyroid oncogene – cancer Osaka thyroid, oncogene – serine/threonine-protein kinase cot – mitogen activated protein kinase kinase kinase 8 – COT proto-oncogene serine/threonine-protein kinase – serine/threonine kinase (Tpl-2)

Mitogen-Activated Protein Kinase Kinase Kinase 8 fulfills a number of functions:

ATP binding – MAP kinase kinase kinase activity – magnesium ion binding – nucleotide binding – protein binding – protein serine/threonine kinase activity – transferase activity – kinase activity – metal ion binding – protein kinase activity

Mitogen-Activated Protein Kinase Kinase Kinase 8 is relevant to the following processes:

cell cycle – protein amino acid phosphorylation – signal transduction

Locations for Mitogen-Activated Protein Kinase Kinase Kinase 8:

cytoplasm – cytosol

Source: NCBI Entrez Gene, Gene Ontology