The following gene names and symbols are associated with antigen MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) across different species:

mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2), mutS homolog 2 (E. coli) (Msh2), mismatch repair protein (MSH2)

Other aliases include:

FCC1, COCA1, HNPCC, LCFS2, HNPCC1, AI788990

On the protein level the following designations are being used for antigen MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli):

mutS homolog 2 – DNA mismatch repair protein Msh2 – mutS protein homolog 2 – mismatch repair protein – MutS-like protein 2

MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) fulfills a number of functions:

ADP binding – ATP binding – ATPase activity – MutLalpha complex binding – centromeric DNA binding – damaged DNA binding – dinucleotide repeat insertion binding – four-way junction DNA binding – guanine/thymine mispair binding – hypoxanthine phosphoribosyltransferase activity – magnesium ion binding – nucleotide binding – oxidized purine DNA binding – protein C-terminus binding – protein homodimerization activity – single guanine insertion binding – single thymine insertion binding – single-stranded DNA binding – DNA binding – mismatched DNA binding – dinucleotide insertion or deletion binding – double-stranded DNA binding – identical protein binding – protein binding

MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli) is relevant to the following processes:

B cell differentiation – B cell mediated immunity – cell cycle arrest – cell motion – determination of adult lifespan – double-strand break repair – germ cell development – in utero embryonic development – intra-S DNA damage checkpoint – isotype switching – maintenance of DNA repeat elements – male gonad development – mismatch repair – negative regulation of DNA recombination – negative regulation of neuron apoptosis – oxidative phosphorylation – positive regulation of helicase activity – postreplication repair – purine nucleotide biosynthetic process – response to DNA damage stimulus – response to UV-B – response to X-ray – somatic hypermutation of immunoglobulin genes – ATP catabolic process – DNA repair – apoptosis – cell cycle – negative regulation of apoptosis – somatic recombination of immunoglobulin gene segments – somatic recombination of immunoglobulin genes involved in immune response – response to amino acid stimulus – response to drug – response to organic cyclic substance – spermatogenesis

Locations for MutS Homolog 2, Colon Cancer, Nonpolyposis Type 1 (E. Coli):

MutSalpha complex – MutSbeta complex – nucleus

Source: NCBI Entrez Gene, Gene Ontology