The following gene names and symbols are associated with antigen Neurofibromin 2 (Merlin) across different species:

neurofibromin 2 (merlin) (NF2), neurofibromatosis 2 (Nf2), neurofibromin 2 (merlin) (Nf2), Merlin (Mer), neurofibromin 2 (bilateral acoustic neuroma) (NF2), merlin (Mer), neurofibromin 2 (merlin) (nf2)

Other aliases include:

ACN, SCH, BANF, merlin, BG01543, Dmerlin, EMR2, mer, DmelCG14228, CG14228, acn, sch, banf, MGC146506

On the protein level the following designations are being used for antigen Neurofibromin 2 (Merlin):

neurofibromin 2 – merlin – schwannomin – schwannomerlin – moesin-ezrin-radixin like – moesin-ezrin-radizin-like protein – neurofibromin 2 (bilateral acoustic neuroma) – neurofibromin-2 – OTTMUSP00000005267 – OTTMUSP00000005268 – OTTMUSP00000005269 – OTTMUSP00000005270 – moesin-ezrin-radixin-like protein – neurofibromatosis 2 – CG14228-PA – Mer-PA – dmerlin – Ezrin-moesin-radixin-2 – D merlin – BG01543 – neurofibromin 2 (merlin)

Neurofibromin 2 (Merlin) fulfills a number of functions:

cytoskeletal protein binding – beta-catenin binding – binding – integrin binding – protein binding – protein domain specific binding

Neurofibromin 2 (Merlin) is relevant to the following processes:

Schwann cell proliferation – actin cytoskeleton organization – cell-cell junction organization – ectoderm development – mesoderm formation – negative regulation of DNA replication – negative regulation of JAK-STAT cascade – negative regulation of MAPKKK cascade – negative regulation of cell migration – negative regulation of cell proliferation – negative regulation of cell-cell adhesion – negative regulation of cell-matrix adhesion – negative regulation of protein kinase activity – negative regulation of tyrosine phosphorylation of Stat3 protein – negative regulation of tyrosine phosphorylation of Stat5 protein – odontogenesis of dentine-containing tooth – positive regulation of stress fiber formation – lens fiber cell differentiation – negative regulation of cell growth – regulation of cell proliferation – positive regulation of stress fiber assembly – regulation of hippo signaling cascade – axis specification – cell-cell signaling – compound eye photoreceptor cell differentiation – decapentaplegic receptor signaling pathway – endocytic recycling – endocytosis – negative regulation of organ growth – olfactory behavior – pole plasm mRNA localization – regulation of cell differentiation – regulation of cell growth – regulation of compound eye retinal cell programmed cell death – regulation of signal transduction

Locations for Neurofibromin 2 (Merlin):

adherens junction – cleavage furrow – cytoplasm – cytoskeleton – early endosome – extrinsic to membrane – filopodium – internal side of plasma membrane – lamellipodium – nucleolus – nucleus – perinuclear region of cytoplasm – plasma membrane – ruffle – cell projection – insoluble fraction – membrane – membrane raft – protein complex – soluble fraction – synapse – apical plasma membrane – fusome

Source: NCBI Entrez Gene, Gene Ontology