The following gene names and symbols are associated with antigen Neurofibromin 2 across different species:

neurofibromin 2 (merlin) (NF2), neurofibromin 2 (NF2), neurofibromin 2 (LOC100357691)

Other aliases include:

ACN, SCH, BANF, NF2

On the protein level the following designations are being used for antigen Neurofibromin 2:

neurofibromin 2 – merlin – schwannomin – schwannomerlin – moesin-ezrin-radixin like – moesin-ezrin-radizin-like protein – neurofibromin 2 (bilateral acoustic neuroma)

Neurofibromin 2 fulfills a number of functions:

cytoskeletal protein binding

Neurofibromin 2 is relevant to the following processes:

Schwann cell proliferation – actin cytoskeleton organization – cell-cell junction organization – ectoderm development – mesoderm formation – negative regulation of DNA replication – negative regulation of JAK-STAT cascade – negative regulation of MAPKKK cascade – negative regulation of cell migration – negative regulation of cell proliferation – negative regulation of cell-cell adhesion – negative regulation of cell-matrix adhesion – negative regulation of protein kinase activity – negative regulation of tyrosine phosphorylation of Stat3 protein – negative regulation of tyrosine phosphorylation of Stat5 protein – odontogenesis of dentine-containing tooth – positive regulation of stress fiber formation

Locations for Neurofibromin 2:

adherens junction – cleavage furrow – cytoplasm – cytoskeleton – early endosome – extrinsic to membrane – filopodium – internal side of plasma membrane – lamellipodium – nucleolus – nucleus – perinuclear region of cytoplasm – plasma membrane – ruffle

Source: NCBI Entrez Gene, Gene Ontology