The following gene names and symbols are associated with antigen Nibrin across different species:

nibrin (NBN), nibrin (Nbn), nibrin (nbn)

Other aliases include:

ATV, NBS, P95, NBS1, AT-V1, AT-V2, FLJ10155, MGC87362, Nbs1, NBN, DKFZp469A0911

On the protein level the following designations are being used for antigen Nibrin:

nibrin – cell cycle regulatory protein p95 – Nijmegen breakage syndrome 1 (nibrin) – p95 protein of the MRE11/RAD50 complex – OTTMUSP00000004959

Nibrin fulfills a number of functions:

damaged DNA binding – protein N-terminus binding – transcription factor binding – ATP-dependent DNA helicase activity

Nibrin is relevant to the following processes:

DNA damage checkpoint – DNA damage response, signal transduction by p53 class mediator – G1/S transition checkpoint – blastocyst growth – cell cycle – cell cycle arrest – cell proliferation – double-strand break repair – in utero embryonic development – isotype switching – meiosis – mitotic cell cycle G2/M transition DNA damage checkpoint – neuromuscular process controlling balance – regulation of DNA replication initiation – regulation of fibroblast proliferation – response to DNA damage stimulus – telomere maintenance – DNA repair – DNA duplex unwinding – mitotic cell cycle G1/S transition checkpoint – positive regulation of kinase activity – positive regulation of protein amino acid autophosphorylation

Locations for Nibrin:

Golgi apparatus – Mre11 complex – chromosome – intracellular – nuclear chromosome, telomeric region – nuclear inclusion body – nucleolus – nucleoplasm – nucleus – replication fork – chromosome, telomeric region

Source: NCBI Entrez Gene, Gene Ontology