The following gene names and symbols are associated with antigen O6-Methylguanine-DNA-Methyltransferase across different species:

O-6-methylguanine-DNA methyltransferase (MGMT)

Other aliases include:

MGMT

On the protein level the following designations are being used for antigen O6-Methylguanine-DNA-Methyltransferase:

O-6-methylguanine-DNA methyltransferase – methylguanine-DNA methyltransferase – O6-methylguanine-DNA methyltransferase – O6-alkylguanine-DNA-alkyltransferase – O6-methylguanine-DNA-methyltransferase

O6-Methylguanine-DNA-Methyltransferase fulfills a number of functions:

DNA binding – DNA-methyltransferase activity – metal ion binding – methylated-DNA-[protein]-cysteine S-methyltransferase activity – transferase activity – zinc ion binding

O6-Methylguanine-DNA-Methyltransferase is relevant to the following processes:

DNA dealkylation – DNA ligation – regulation of caspase activity – response to DNA damage stimulus

Locations for O6-Methylguanine-DNA-Methyltransferase:

nucleoplasm – nucleus

Source: NCBI Entrez Gene, Gene Ontology

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibody (ABIN125221) cited in Journal of clinical oncology : official journal of the American Society of Clinical Oncology

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibody (ABIN125221) cited in Annals of surgical oncology

anti-O6-Methylguanine-DNA-Methyltransferase (MGMT) antibody (ABIN125221) cited in British journal of cancer

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