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Obscurin (OBSCN)
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Host
Mouse 1

Clonality

Antigen Obscurin (OBSCN)

4 Products Sort by

Obscurin (OBSCN) antibody

Mouse, Polyclonal
ISO
Reactivity:Human
Application:EIA, WB
ABIN529547
Ships within 7 to 10 Business Days
260.00 $
50 µl

Obscurin (OBSCN) ELISA Kit

ISO
Reactivity:Human
ABIN422306
Ships within 7 to 10 Business Days
864.00 $
96T

Obscurin (OBSCN) ELISA Kit

ISO
Reactivity:Mouse (Murine)
ABIN429640
Ships within 7 to 10 Business Days
883.20 $
96T

Obscurin (OBSCN) ELISA Kit

ISO
Reactivity:Rat (Rattus)
ABIN436414
Ships within 7 to 10 Business Days
921.60 $
96T
1
Antigen Profile  
Obscurin
GENE ID SPECIES
84033 Homo sapiens
380698 Mus musculus
420395 Gallus gallus
457798 Pan troglodytes
537193 Bos taurus

The following gene names and symbols are associated with antigen Obscurin across different species:

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (OBSCN), obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF (Obscn)

Other aliases include:

UNC89, ARHGEF30, FLJ14124, KIAA1556, KIAA1639, MGC120409, MGC120410, MGC120411, MGC120412, MGC138590, DKFZp666E245, Gm878, BC046431, MGC51514, OTTMUSG00000005786, MGC166429

On the protein level the following designations are being used for antigen Obscurin:

obscurin – obscurin-MLCK – obscurin-RhoGEF – obscurin-myosin light chain kinase – obscurin, myosin light chain kinase – obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

Obscurin fulfills a number of functions:

ATP binding – Rho guanyl-nucleotide exchange factor activity – guanyl-nucleotide exchange factor activity – metal ion binding – nucleotide binding – protein binding – protein serine/threonine kinase activity – protein tyrosine kinase activity – structural constituent of muscle – titin binding – transferase activity – ankyrin binding – kinase activity – protein kinase activity

Obscurin is relevant to the following processes:

apoptosis – cell differentiation – induction of apoptosis by extracellular signals – multicellular organismal development – nerve growth factor receptor signaling pathway – protein phosphorylation – regulation of Rho protein signal transduction – regulation of small GTPase mediated signal transduction – small GTPase mediated signal transduction

Locations for Obscurin:

M band – Z disc – cytoplasm – cytosol – intracellular – myofibril – striated muscle myosin thick filament

Source: NCBI Entrez Gene, Gene Ontology