Quantity: 25 ul. Description: PARP is a 116 kDa nuclear protein which is strongly activated by DNA strand breaks. PARP plays a role in DNA repair as well as in other cellular processes, including DNA replication, cell proliferation and differentiation. During apoptosis, ICE family members, such as caspas... Immunogen: Synthetic peptide: GVDEVAKKKSK...  More »

Quantity: 500 ul. Description: Proteolysis of PARP to its stable 85 kD fragment is an early marker of apoptosis and is mediated by Caspase (CPP32) protein. PARP uses nicotinamide adenine dinucleotide (oxidized form) as a substrate to catalyze the transfer of ADP-ribose to a variety of nuclear acceptors. Immunogen: A synthetic peptide from the N... Specificity: This antibody reacts with a 116 kDa protein, known...

Quantity: 100 ug. Clone: C-2-10. Format: Purified. Description: 100 ug purified mouse IgG1 (clone C-2-10). Detects 116 kDa PARP and the 85 kDa apoptosis related cleavage fragment. Reacts with human/mouse/rat/monkey/hamster. Works well in Western blotting/Immunocytochemistry/ELISA. Specificity: Detects 116 kDa PARP and the 85 kDa apoptosis rela...

Quantity: 7ml. Description: Ig Fraction, Aff.Pur., Prediluted

Quantity: 100 µg. Clone: C-2-10. Description: PARP is a highly conserved nuclear enzyme present in higher eukaryotes. The enzyme is a Zn 2+ -dependent DNA binding protein that recognizes DNA strand breaks and is implicated in DNA repair and in apoptosis responses of cells. As a marker for apoptosis, it has been shown th... Immunogen: Immunogen used was purified ca... Specificity: The antibody recognizes the 116 kDa PARP and the 8...  More »

Quantity: 100 ug. Clone: 5A5. Format: Liquid. Description: Mouse monoclonal [5A5] to PARP Immunogen: Recombinant fragment (Human).

Quantity: 100 ul. Description: Poly(ADP-ribose) polymerase (PARP), a nuclear enzyme often termed a molecular nick sensor, recognizes and binds to DNA single or double strand breaks through the N-terminal DNA binding domain sensor. The activation of PARP is one of the first responses to DNA strand interrup... Immunogen: Synthetic peptide, correspondi... Specificity: Recognizes 116 kDa PARP and the 85 kDa apoptosis-r...  More »

Quantity: 100 ug. Clone: A6-4-12. Format: Liquid. Description: Recognises poly (ADP-ribose) polymerase (PARP), a 116kD nuclear enzyme that has been shown to be cleaved during apoptosis. Immunogen: human PARP Specificity: human PARP

Quantity: 100 µg. Clone: 5A5. Format: Purified. Description: PARP (Poly (ADP-ribose) polymerase) is a 113 kD nuclear protein that can exist as a homo- or hetero-dimer. This protein acts as a molecular nick sensor and functions in base excision repair, poly(ADP-ribosyl)ation of acceptor proteins involved in chromatin architecture and D... Immunogen: Recombinant (partial), N-termi... Specificity: Component of a base excision repair complex contai...  More »

Quantity: 100 µg. Clone: 5A5. Conjugate: Biotin. Description: PARP (Poly (ADP-ribose) polymerase) is a 113 kD nuclear protein that can exist as a homo- or hetero-dimer. This protein acts as a molecular nick sensor and functions in base excision repair, poly(ADP-ribosyl)ation of acceptor proteins involved in chromatin architecture and D... Immunogen: Recombinant (partial), N-termi... Specificity: Component of a base excision repair complex contai...  More »