The following gene names and symbols are associated with antigen PYD and CARD Domain Containing across different species:

PYD and CARD domain containing (PYCARD), PYD and CARD domain containing (Pycard)

Other aliases include:

ASC, TMS, TMS1, CARD5, TMS-1, MGC10332, Asc, PYCARD

On the protein level the following designations are being used for antigen PYD and CARD Domain Containing:

PYD and CARD domain containing – caspase recruitment domain protein 5 – target of methylation-induced silencing-1 – apoptosis-associated speck-like protein containing a CARD

PYD and CARD Domain Containing fulfills a number of functions:

Pyrin domain binding – caspase activator activity – cysteine-type endopeptidase activity – protein binding – protein homodimerization activity

PYD and CARD Domain Containing is relevant to the following processes:

activation of caspase activity – induction of apoptosis – positive regulation of NF-kappaB transcription factor activity – positive regulation of interleukin-1 beta secretion – proteolysis – regulation of apoptosis – signal transduction – tumor necrosis factor-mediated signaling pathway – inflammatory response – regulation of caspase activity

Locations for PYD and CARD Domain Containing:

IkappaB kinase complex – cytoplasm – intracellular – cytosol – extracellular region

Source: NCBI Entrez Gene, Gene Ontology